Background and objectives: Different adjuvants have been used to prolong intrathecal
spinal anesthesia, with the possible advantages of delayed onset of post-operative pain …

Purpose Dexmedetomidine, a selective α2-adrenoceptor agonist, has analgesic and
sedative effects. The purpose of this study was to investigate the effects of small, single-dose …

Background: Alpha 2-adrenergic agonists have synergistic action with local anesthetics and
may prolong the duration of sensory, motor blockade and postoperative analgesia obtained …

Background: Regional anesthesia is the preferred technique for most of lower abdominal
and lower limb surgeries. For decades, lignocaine had been the local anesthetic of choice …

Background: Adjuvants in spinal anesthesia extends not only the duration of surgical
anesthesia but also provides postoperative analgesia. This study aimed at comparing …

Background: The supplementation of local anaesthetics with adjuvants to improve the
efficacy of subarachnoid block has been recognised since long. The most preferred drug …

Background Dexmedetomidine was shown to improve bupivacaine spinal anesthesia.
Objective The aim of this study was to compare between intrathecal and intravenous (iv) …

Background: Prolongation of spinal analgesia extends not only the duration of surgical
anaesthesia but also provides postoperative analgesia. The effects of adjuvants like …

Introduction: Various adjuvants to local anaesthetic are used to improve quality and duration
of spinal anaesthesia. Dexmedetomidine, a novel alpha-2 adrenergic agonist, has been …

Background and goals. Oral, intrathecal, and intravenous clonidine prolong bupivacaine
spinal anesthesia. There is no information on the effect of intravenous dexmedetomidine to …