Lipoprotein (a): more interesting than ever after 50 years
Despite the wealth of epidemiologic evidence supporting Lp (a) concentration as a CHD risk
factor, the lack of a definitive functional mechanism involving an Lp (a)-dependent pathway …
factor, the lack of a definitive functional mechanism involving an Lp (a)-dependent pathway …
Lipoprotein (a): a genetic marker for cardiovascular disease and target for emerging therapies
A Cesaro, A Schiavo, E Moscarella… - Journal of …, 2021 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is an established cardiovascular risk factor, and growing
evidence indicates its causal association with atherosclerotic disease because of the …
evidence indicates its causal association with atherosclerotic disease because of the …
Molecular basis of congenital lp (a) deficiency: a frequent apo (a)'null'mutation in caucasians
M Ogorelkova, A Gruber… - Human molecular …, 1999 - academic.oup.com
High plasma concentrations of lipoprotein (a)[Lp (a)], a covalent low-density lipoprotein-
apolipoprotein (a)[apo (a)] complex, are associated with coronary heart disease and stroke …
apolipoprotein (a)[apo (a)] complex, are associated with coronary heart disease and stroke …
Lipoprotein (a)—the crossroads of atherosclerosis, atherothrombosis and inflammation
S Ugovšek, M Šebeštjen - Biomolecules, 2021 - mdpi.com
Increased lipoprotein (a)(Lp (a)) levels are an independent predictor of coronary artery
disease (CAD), degenerative aortic stenosis (DAS), and heart failure independent of CAD …
disease (CAD), degenerative aortic stenosis (DAS), and heart failure independent of CAD …
Impact of apolipoprotein (a) isoform size on lipoprotein (a) lowering in the HPS2-THRIVE study
S Parish, JC Hopewell, MR Hill… - Circulation: Genomic …, 2018 - Am Heart Assoc
Background: Genetic studies have shown lipoprotein (a)(Lp [a]) to be an important causal
risk factor for coronary disease. Apolipoprotein (a) isoform size is the chief determinant of Lp …
risk factor for coronary disease. Apolipoprotein (a) isoform size is the chief determinant of Lp …
Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans
Lipoprotein (a)(Lp (a)) is an important causal cardiovascular risk factor, with serum Lp (a)
levels predicting atherosclerotic heart disease and genetic determinants of Lp (a) levels …
levels predicting atherosclerotic heart disease and genetic determinants of Lp (a) levels …
Apolipoprotein (a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants
S Erqou, A Thompson, E Di Angelantonio… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to assess the association of apolipoprotein
(a)(apo [a]) isoforms with cardiovascular disease risk. Background: Although circulating …
(a)(apo [a]) isoforms with cardiovascular disease risk. Background: Although circulating …
Lipoprotein (a): a genetic risk factor for premature coronary heart disease
AM Scanu - JAMA, 1992 - jamanetwork.com
Lipoprotein (a)(Lp [a]) can be defined as a lipoprotein particle having as a protein moiety
apolipoprotein B-100 (the protein associated with low-density lipoprotein) disulfide-linked to …
apolipoprotein B-100 (the protein associated with low-density lipoprotein) disulfide-linked to …
Ascertainment bias in the association between elevated lipoprotein (a) and familial hypercholesterolemia
M Trinder, ML DeCastro, H Azizi, L Cermakova… - Journal of the American …, 2020 - jacc.org
Background Lipoprotein (a) is an atherogenic low-density lipoprotein–like particle and
circulating levels are largely determined by genetics. Patients with familial …
circulating levels are largely determined by genetics. Patients with familial …
Association of LPA variants with risk of coronary disease and the implications for lipoprotein (a)-lowering therapies: a Mendelian randomization analysis
Importance Human genetic studies have indicated that plasma lipoprotein (a)(Lp [a]) is
causally associated with the risk of coronary heart disease (CHD), but randomized trials of …
causally associated with the risk of coronary heart disease (CHD), but randomized trials of …