Objectives This study investigated the prevalence and characteristics of mcr-1-harbouring
Escherichia coli isolated from chickens in central China from 2014 to 2019. Methods A total …

Antimicrobial resistance to colistin has emerged worldwide threatening the efficacy of one of
the last-resort antimicrobials used for the treatment of multidrug-resistant Enterobacteriacea …

The objective of this study was to determine the minimal inhibitory concentration of colistin
for Escherichia coli from food animals and the possible underlying colistin resistance …

Colistin is the last line of defense for the treatment of multidrug-resistant gram-negative
bacterial infections. However, colistin resistance is gradually increasing worldwide, with …

The emergence of the plasmid-mediated colistin resistance gene mcr-1 is threatening the
last-line role of colistin in human medicine. With mcr-1-positive Escherichia coli (E. coli) …

Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-
resistant Gram-negative bacterial infections. The recent global dissemination of mobilized …

Colistin is one of the last-line drugs against difficult to treat and multidrug-resistant Gram-
negative bacteria. The emergence of mobile colistin resistance gene m cr-1 increased …

Abstract Objectives In November 2015, a plasmid-mediated colistin resistance, MCR-1, was
described in animals, food and humans in China, and it was considered as a potential …

Increasing colistin resistance is a global concern because colistin is used as a last resort for
the treatment of carbapenem-resistant Enterobacteriaceae infections. The plasmid-mediated …

Considering the serious threat to food safety and public health posed by pathogens with
colistin resistance, colistin was banned as a growth promoter in 2017 in China. In recent …