A new horizon in the treatment of right ventricular failure and pulmonary hypertension associated with acute respiratory distress syndrome?

RW Carlson, L Emmans - Critical care medicine, 2006 - journals.lww.com
Sepsis is an increasingly com-mon and lethal condition among hospitalized patients. It
remains one of the most difficult conditions we encounter as intensivists, in part because of …

Measuring ventilation through defibrillator pads… First steps toward avoidance of “death by hyperventilation” during cardiopulmonary resuscitation?

V Nadkarni - Critical care medicine, 2006 - journals.lww.com
Sepsis is an increasingly com-mon and lethal condition among hospitalized patients. It
remains one of the most difficult conditions we encounter as intensivists, in part because of …

Sepsis—New strategies with host defense peptides?

L Steinstraesser - Critical care medicine, 2004 - journals.lww.com
Sepsis continues to kill hundreds of thousands of patients each year and is associated with
a high socioeconomic impact of $17 billion in the United States. Sepsis results when the …

Improving outcomes in septic shock—Can we define causality and find more efficacious treatments?

PD Mongan - Critical care medicine, 2005 - journals.lww.com
The death toll for septic shock is still unacceptably high. Even if one could argue that there is
a limit lowering its mortality rate, there is definitively room for new breakthroughs …

Sepsis: the future is bright

GS Martin - Critical care medicine, 2006 - journals.lww.com
Sepsis is an increasingly common and lethal condition among hospitalized patients. It
remains one of the most difficult conditions we encounter as intensivists, in part because of …

New drug for sepsis on the cheap?

H Sauthoff, JG Hay - Critical Care Medicine, 2015 - journals.lww.com
Many biological pathways are involved in the evolution of the clinical condition of sepsis.
Infection triggers complex and variable host responses. Proinflammatory mechanisms can …

Are recruiting maneuvers needed when ventilating acute respiratory distress syndrome?

JJ Marini - Critical care medicine, 2003 - journals.lww.com
Human sepsis reflects a com-plex systemic process in which alterations occur in every
metabolic and regulatory system that has been studied (1). Clinical data demonstrate …

Hemodynamic support in septic shock: Is restoring a normal blood pressure the right target?

D Bracco, MJ Dubois - Critical care medicine, 2005 - journals.lww.com
The death toll for septic shock is still unacceptably high. Even if one could argue that there is
a limit lowering its mortality rate, there is definitively room for new breakthroughs …

Orange You Wishing There Were Definitive Randomized Controlled Trials Already?

DN Hager, A Agarwal, B Rochwerg - Critical care medicine, 2021 - journals.lww.com
Sepsis affects approximately 1,750,000 people in the United States each year with half
requiring ICU admission and 20–30% of cases resulting in death (1). Among those who …

Cardiovascular dysfunction of sepsis: A nitric oxide-and l-arginine-deficient state?

PE Marik - Critical care medicine, 2003 - journals.lww.com
Sepsis is characterized by a high cardiac output, biventricular systolic and diastolic
dysfunction, and peripheral vasodilation together with a diffuse microvascular injury (1) …