Aquaporin-4 (AQP4) is a water channel expressed on astrocytic endfeet in the brain. The
role of AQP4 has been studied in health and in a range of pathological conditions. Interest in …

About 80% of the brain is water. This review discusses the importance of the three brain
water-channel proteins (AQP1, AQP4, AQP9) in brain physiology. AQP1 is expressed in the …

Summary Aquaporin 4 (AQP 4) is the main water channel in the central nervous system
(CNS) and specifically localized to astrocyte processes. Recent studies indicate that AQP 4 …

The aquaporins (AQPs) are plasma membrane water-transporting proteins. AQP4 is the
principal member of this protein family in the CNS, where it is expressed in astrocytes and is …

Abstract Aquaporin-4 (AQP4) is the most abundantly expressed aquaporin in the central
nervous system (CNS) and is an integral part of the glymphatic system that cannot be …

Abstract Aquaporin-4 (AQP4) is a water-selective transporter expressed in astrocytes
throughout the central nervous system, as well as in kidney, lung, stomach and skeletal …

Abstract Aquaporin 4 (AQP4), one of the water channel proteins on the plasma membrane of
astrocytes, is up-regulated in various conditions with brain edema. Possible participation of …

The aquaporin channel family was first considered as a family of water channels, however it
is now clear that some of these channels are also permeable to small solutes such glycerol …

Background The presence of water channel proteins, aquaporins (AQPs), in the brain led to
intense research in understanding the underlying roles of each of them under normal …

Aquaporin-4 (AQP4) is a predominant water channel protein in mammalian brains that is
distributed with the highest density in the perivascular and subpial astrocyte end-feet. AQP4 …