Metabolic engineering in hairy roots: An outlook on production of plant secondary metabolites

D Bagal, AA Chowdhary, S Mehrotra, S Mishra… - Plant Physiology and …, 2023 - Elsevier
Plants are one of the vital sources of secondary metabolites. These secondary metabolites
have diverse roles in human welfare, including therapeutic implication. Nevertheless …

Engineering secondary metabolite production in hairy roots

S Chandra, R Chandra - Phytochemistry reviews, 2011 - Springer
Plants are a rich source of valuable secondary metabolites. Plant cell culture technologies
developed in the past as possible tools for secondary metabolites production. In most cases …

Bioengineering hairy roots: phytoremediation, secondary metabolism, molecular pharming, plant-plant interactions and biofuels

P Habibi, MFG De Sa, A Makhzoum, S Malik… - Sustainable agriculture …, 2017 - Springer
Hairy root cultures are an efficient tool to understand plant biology, biotechnology and other
applied sciences. In particular such cultures have revealed many cues of plant cells related …

Hairy root cultures for secondary metabolites production

L Pistelli, A Giovannini, B Ruffoni, A Bertoli… - Bio-farms for …, 2010 - Springer
Hairy roots (HRs) are differentiated cultures of transformed roots generated by the infection
of wounded higher plants with Agrobacterium rhizogenes. This pathogen causes the HR …

Biotechnological interventions for production of therapeutic secondary metabolites using hairy root cultures of medicinal plants

V Srivastava, S Mehrotra, PK Verma - Current developments in …, 2017 - Elsevier
The repository of molecules (secondary metabolites) in plants have been identified as an
effective candidate to cure human diseases. This immense potential is continuously being …

The current status and future applications of hairy root cultures

N Dhiman, V Patial, A Bhattacharya - Biotechnological Approaches for …, 2018 - Springer
Hairy roots are produced when the soil phytopathogen, Agrobacterium rhizogenes, infects a
host plant. Just like normal roots, the hairy roots have the capacity to absorb target elements …

Production and metabolic engineering of bioactive substances in plant hairy root culture

ML Zhou, XM Zhu, JR Shao, YX Tang… - Applied microbiology and …, 2011 - Springer
In the past three decades, hairy roots research for the production of valuable biological
active substances has received a lot of attention. The addition of knowledge to enhance the …

Using hairy roots for production of valuable plant secondary metabolites

L Tian - Filaments in bioprocesses, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Plants synthesize a wide variety of natural
products, which are traditionally termed secondary metabolites and, more recently, coined …

Biotechnological exploration of transformed root culture for value-added products

M Shi, P Liao, SH Nile, MI Georgiev, G Kai - Trends in Biotechnology, 2021 - cell.com
Medicinal plants produce valuable secondary metabolites with anticancer, analgesic,
anticholinergic or other activities, but low metabolite levels and limited available tissue …

Hairy root culture for in vitro production of secondary metabolites: a promising biotechnological approach

RS Singh, T Chattopadhyay, D Thakur, N Kumar… - … for Medicinal and …, 2018 - Springer
Hairy root culture (HRC)-based in vitro production system has become a promising
biotechnological approach in recent years. The hairy root formation is the result of …