Transgenic mice were developed which expressed human lactoferrin (hLF) in the mammary
gland. This was achieved by using regulatory elements of bovine β-casein gene, rabbit β …

In our previous study, transgenic mice were generated that expressed human lactoferrin
(hLF) in milk using cDNA under control of the 2kb bovine ƒÀ-casein promoter. The …

In our previous study, using a bovine β-casein/human lactoferrin hybrid gene, transgenic
mice were generated to target the expression of human lactoferrin (hLF) into the mammary …

The expression of human lactoferrin (hLF) in the milk of transgenic mice is described.
Regulatory sequences derived from the bovine αS1-casein gene were fused to the coding …

The aim of this study was to construct a mammary gland-specific expressional vector pBC1-
hLF-Neo for Human Lactoferrin (hLF) gene and then investigate its expression in the …

One major drawback in research of animal mammary gland bioreactors is the low production
rate of high-expressing transgenic animals due to position effects. To obtain high and stable …

To elevate the expression frequency of transgenes in transgenic mice, the chicken lysozyme
matrix attachment region (MAR) sequence was used by combining it with a transgene. The …

It is very important to develop an effective, specific, and robust expression cassette that
ensures a high level of expression in the mammary glands. In this study, we designed and …

There is growing interest in the application of lactoferrin (LF) as a drug or food additive for
animals and humans. The objective of this study was to produce transgenic cloned goats …

The regulatory region of the bovine α S1 casein gene was used to obtain two genetic
constructs for expression of human lactoferrin in the mammary gland of transgenic animals …