Virulence mechanisms and Cryptococcus neoformans pathogenesis

JA Alspaugh - Fungal Genetics and Biology, 2015 - Elsevier
The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …

The interplay of phenotype and genotype in Cryptococcus neoformans disease

S Altamirano, KM Jackson, K Nielsen - Bioscience Reports, 2020 - portlandpress.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …

[HTML][HTML] The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans

JN Steenbergen, A Casadevall - Microbes and infection, 2003 - Elsevier
The origin of virulence in environmental fungi that have no requirement for animal hosts in
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …

Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence

KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …

The tools for virulence of Cryptococcus neoformans

C Coelho, AL Bocca, A Casadevall - Advances in applied microbiology, 2014 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

The cause and effect of Cryptococcus interactions with the host

ER Ballou, SA Johnston - Current opinion in microbiology, 2017 - Elsevier
Upon Cryptococcus neoformans infection of the host lung, the fungus enters a nutrient poor
environment and must adapt to a variety of host-specific stress conditions (temperature …

Cryptococcus neoformans: A sugar-coated killer with designer genes

JR Perfect - FEMS Immunology & Medical Microbiology, 2005 - academic.oup.com
Cryptococcus neoformans has become a common central nervous system pathogen as the
immunocompromised populations enlarge world-wide. This encapsulated yeast has …

Identification of ENA1 as a Virulence Gene of the Human Pathogenic Fungus Cryptococcus neoformans through Signature-Tagged Insertional Mutagenesis

A Idnurm, FJ Walton, A Floyd, JL Reedy… - Eukaryotic cell, 2009 - Am Soc Microbiol
ABSTRACT A library of more than 4,500 signature-tagged insertion mutants of the human
pathogenic fungus Cryptococcus neoformans was generated, and a subset was screened in …

The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …