Superparamagnetic iron oxide nanoparticles (SPIONs): synthesis and surface modification techniques for use with MRI and other biomedical applications

S Yoffe, T Leshuk, P Everett, F Gu - Current pharmaceutical …, 2013 - ingentaconnect.com
Superparamagnetic iron oxide nanoparticles (SPIONs) comprise a fundamental technology
class within the emerging field of nanomedicine, and have been extensively researched for …

Epirubicin‐loaded superparamagnetic iron‐oxide nanoparticles for transdermal delivery: cancer therapy by circumventing the skin barrier

Y Rao, W Chen, X Liang, Y Huang, J Miao, L Liu, Y Lou… - Small, 2015 - Wiley Online Library
The transdermal administration of chemotherapeutic agents is a persistent challenge for
tumor treatments. A model anticancer agent, epirubicin (EPI), is attached to functionalized …

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

M Suciu, CM Ionescu, A Ciorita… - Beilstein Journal of …, 2020 - beilstein-journals.org
Superparamagnetic iron oxide nanoparticles (SPIONs) have unique properties with regard
to biological and medical applications. SPIONs have been used in clinical settings although …

Superparamagnetic iron oxide nanocargoes for combined cancer thermotherapy and MRI applications

ND Thorat, OM Lemine, RA Bohara, K Omri… - Physical Chemistry …, 2016 - pubs.rsc.org
Nanoparticle-based cancer diagnosis–therapy integrative systems (cancer theranostics)
represent an emerging approach in oncology. To address this issue in the present work iron …

[HTML][HTML] Magnetism in drug delivery: The marvels of iron oxides and substituted ferrites nanoparticles

NN Al-Rawi, BA Anwer, NH Al-Rawi, AT Uthman… - Saudi Pharmaceutical …, 2020 - Elsevier
In modern drug delivery, seeking a drug delivery system (DDS) with a modifiable skeleton
for proper targeting of loaded actives to specific sites in the body is of extreme importance for …

Superparamagnetic iron oxide nanoparticles for magnetic hyperthermia: Recent advancements, molecular effects, and future directions in the omics era

C Pucci, A Degl'Innocenti, MB Gümüş… - Biomaterials Science, 2022 - pubs.rsc.org
Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted attention in the
biomedical field thanks to their ability to prompt hyperthermia in response to an alternated …

Iron oxide nanoparticles for targeted cancer imaging and diagnostics

JE Rosen, L Chan, DB Shieh, FX Gu - … : Nanotechnology, Biology and …, 2012 - Elsevier
Superparamagnetic iron oxide nanoparticles (SPIONs) have proven to be highly effective
contrast agents for the magnetic resonance imaging diagnosis of solid tumors. This review …

Development of multifunctional hyaluronan-coated nanoparticles for imaging and drug delivery to cancer cells

MH El-Dakdouki, DC Zhu, K El-Boubbou… - …, 2012 - ACS Publications
Currently, there is high interest in developing multifunctional theranostic platforms for cancer
monitoring and chemotherapy. Herein, we report hyaluronan (HA)-coated …

Superparamagnetic iron oxide nanoparticles for MR imaging and therapy: design considerations and clinical applications

R Jin, B Lin, D Li, H Ai - Current opinion in pharmacology, 2014 - Elsevier
Highlights•Surface engineering of SPION determines their in vivo performance.•Targeting
mechanisms of SPION imaging are summarized.•Clinical trial information related to SPION …

Enhanced cell uptake of superparamagnetic iron oxide nanoparticles functionalized with dendritic guanidines

AL Martin, LM Bernas, BK Rutt, PJ Foster… - Bioconjugate …, 2008 - ACS Publications
Magnetic resonance imaging (MRI) is a powerful tool for the diagnosis of disease and the
study of biological processes such as cancer metastasis and inflammation …