Background: There have been many studies in recent years concerning the role of nitric
oxide (NO) in acute renal failure (ARF). In this study, the effects of the inhibition or the …

Different nitric oxide synthase (NOS) isoforms are found in the kidney. Some studies
provided evidences that increased endothelial NOS (eNOS) activity leads to restoration of …

We evaluated the effect of acute or chronic nitric oxide (NO) synthesis activation or inhibition
in rats with gentamicin-induced acute renal failure. Rats received gentamicin 100 mg/kg per …

The present experiments were designed to assess the effect of inhibiting NO synthesis on
the renal failure induced in rats by treatment with high doses of gentamicin. Eighteen Wistar …

GENTA nephrotoxicity is likely to be caused, among other factors, by an increase of
vasoconstrictors or a decrease of vasodilators such as NO. Few days after discontinuing …

Nephrotoxicity results from an abrupt decline in glomerular functions of the kidney and is
regarded as a major cause of concern for limiting therapeutic uses of gentamicin in hospital …

Besides other mechanisms, nitric oxide (NO) plays a major role in maintaining the high renal
blood flow (RBF) and is also involved in the regulation of glomerular hemodynamics and …

Background. In recent studies increased amounts of nitric oxide (NO) and apoptosis have
been implicated in various pathological conditions in the kidney. We have studied the role of …

Nitric oxide (NO) is generated from L-arginine (Arg) by different isoforms of nitric oxide
synthase (NOS) and plays a major role in maintaining the high basal renal blood flow. NO …

We investigated the effects of orally supplemented l-arginine, the substrate of nitric oxide
(NO) and Nω-nitro-l-arginine methyl ester (l-NAME), a nitric oxide-synthase inhibitor in …