Arthritic diseases cause enormous burdens in terms of pain, crippling, and disability.
Osteoarthritis (OA), the most common form of arthritis, is characterized by a slow progressive …

Human osteoarthritis is a systemic musculoskeletal disorder involving activation of innate
and adaptive immune systems accompanied by inflammation exemplified by the elevated …

Osteoarthritis, a degenerative joint disease, is the most disabling condition of the Western
world. It affects first and foremost the articular cartilages and leads to a molecular and …

Osteoarthritis (OA) has long been considered the unique consequence of a wear and tear
process leading to cartilage degradation. Indeed, it is true that excessive mechanical stress …

Rheumatoid arthritis is a chronic autoimmune syndrome associated with several genetic,
epigenetic, and environmental factors affecting the articular joints contributing to cartilage …

Osteoarthritis (OA) is the most common chronic disease of human joints. The basis of
pathologic changes involves all the tissues forming the joint; already, at an early stage, it has …

[Frontiers in Bioscience 4, d662-670, October 15, 1999] 662 An introduction to the pathophysiology
of osteoarthritis A. Robin Po Page 1 [Frontiers in Bioscience 4, d662-670, October 15, 1999] …

Osteoarthritis (OA) results from interaction among a number of complex biologic processes,
both degradative and reparative. There is a growing trend to view the joint as an entire …

Morphological changes observed in OA include cartilage erosion as well as a variable
degree of synovial inflammation. Current research attributes these changes to a complex …

In the pathogenesis of several rheumatic diseases, such as rheumatoid arthritis,
spondyloarthritis, osteoarthritis, osteoporosis, alterations in osteoblast growth, differentiation …