Involvement of integrins in fimbriae‐mediated binding and invasion by Porphyromonas gingivalis

Ö Yilmaz, K Watanabe, RJ Lamont - Cellular microbiology, 2002 - Wiley Online Library
Interaction between the major fimbriae of Porphyromonas gingivalis and gingival epithelial
cells is important for bacterial adhesion and invasion. In this study, we identified integrins as …

Porphyromonas gingivalis Fimbriae Proactively Modulate β2 Integrin Adhesive Activity and Promote Binding to and Internalization by Macrophages

G Hajishengallis, M Wang, E Harokopakis… - Infection and …, 2006 - Am Soc Microbiol
In monocytes, the fimbriae of the oral pathogen Porphyromonas gingivalis activate cross talk
signaling from Toll-like receptor 2 (TLR2) to the β2 integrin CD11b/CD18, leading to the …

Invasion of Epithelial Cells and Proteolysis of Cellular Focal Adhesion Components by Distinct Types of Porphyromonas gingivalis Fimbriae

I Nakagawa, H Inaba, T Yamamura, T Kato… - Infection and …, 2006 - Am Soc Microbiol
Porphyromonas gingivalis fimbriae are classified into six types (types I to V and Ib) based on
the fimA genes encoding FimA (a subunit of fimbriae), and they play a critical role in …

Gingival epithelial cell signalling and cytoskeletal responses to Porphyromonas gingivalis invasion

O Yilmaz, PA Young, RJ Lamont… - Microbiology, 2003 - microbiologyresearch.org
Porphyromonas gingivalis, an oral pathogen, can internalize within primary gingival
epithelial cells (GECs) through an invasion mechanism mediated by interactions between P …

A role for fimbriae in Porphyromonas gingivalis invasion of oral epithelial cells

T Njoroge, RJ Genco, HT Sojar, N Hamada… - Infection and …, 1997 - Am Soc Microbiol
Isogenic mutants of Porphyromonas gingivalis which differ in the expression of fimbriae
were used to examine the contribution of fimbriae in invasion of a human oral epithelial cell …

Role of fimbriae in Porphyromonas gingivalis invasion of gingival epithelial cells

A Weinberg, CM Belton, Y Park… - Infection and …, 1997 - Am Soc Microbiol
Porphyromonas gingivalis is a periodontal pathogen capable of invading primary cultures of
normal human gingival epithelial cells (NHGEC). Involvement of P. gingivalis fimbriae in the …

Porphyromonas gingivalis Fimbriae Bind to Cytokeratin of Epithelial Cells

HT Sojar, A Sharma, RJ Genco - Infection and immunity, 2002 - Am Soc Microbiol
The adherence of Porphyromonas gingivalis to host cells is likely a prerequisite step in the
pathogenesis of P. gingivalis-induced periodontal disease. P. gingivalis binds to and …

Fimbria-Dependent Activation of Cell Adhesion Molecule Expression in Porphyromonas gingivalis-Infected Endothelial Cells

M Khlgatian, H Nassar, HH Chou… - Infection and …, 2002 - Am Soc Microbiol
Porphyromonas gingivalis is an oral pathogen that has recently been associated with
chronic inflammatory diseases such as atherosclerosis. The strength of the epidemiological …

Virulence of Porphyromonas gingivalis is altered by substitution of fimbria gene with different genotype

T Kato, S Kawai, K Nakano, H Inaba… - Cellular …, 2007 - Wiley Online Library
Porphyromonas gingivalis is a periodontal pathogen whose fimbriae are classified into six
genotypes based on the diversity of the fimA genes encoding each fimbria subunit. It was …

Porphyromonas gingivalis Gingipains and Adhesion to Epithelial Cells

T Chen, K Nakayama, L Belliveau… - Infection and …, 2001 - Am Soc Microbiol
Porphyromonas gingivalis is one of the principal organisms associated with adult
periodontitis. Bacterial surface proteins such as fimbriae and gingipain hemagglutinin …