Purpose Liver is the major site of biotransformation for exogenous toxins, in having a
defense system against oxidative stress as well as cytochrome P450 system. Isoliquiritigenin …

Emodin (EMO), the main bioactive component of Polygonum multiflorum, Rheum palmatum,
Aloe vera and Cassia acutifolia, can cause severe hepatotoxicity. Isoliquiritigenin (ISL), a …

Isoliquiritigenin, a flavonoid found in licorice, has been considered as an antioxidive and
hepato-protective agent. Recent studies have shown that a possible mechanism for triptolide …

Glycyrrhizae radix (G. radix) has been demonstrated to have hepatoprotective properties.
This study determined the therapeutic effects of isoliquiritigenin (isoLQ) in G. radix, against …

Isoliquiritigenin (ILQ), a flavonoid obtained from Glycyrrhizae species, has an antioxidant
effect. This study investigated the potential of ILQ for inhibiting liver X receptor-α (LXRα) …

Oxidative stress plays a critical role in drug-induced liver injury. In recent years, liquiritigenin
(LQ), a natural flavonoid distributed in Glycyrrhizae Radix et Rhizoma (Gan Cao), shows …

Oxidative stress could lead to a variety of body dysfunctions, including neurodegeneration
and cancer, which are closely associated with intracellular signal transducers such as …

Hepatic sinusoidal obstruction syndrome (HSOS) is a serious and life-threatening liver
disease. Liquiritigenin (LG) and liquiritin (LQ) are natural flavonoids distributed in …

Glycyrrhizae radix has been widely accepted as a functional food in Asia. Isoliquiritigenin is
a characteristic bioactive chemical in this medicinal plant. In this work, the neuroprotective …

AIM OF THE STUDY: The study was aimed to investigate the protective effect against
hepatic injury induced by CCl4 for the ethanolic extract of FZJ. MATERIALS AND …