[HTML][HTML] Hematopoietic stem/progenitor cell proliferation and differentiation is differentially regulated by high-density and low-density lipoproteins in mice
Y Feng, S Schouteden, R Geenens, V Van Duppen… - PloS one, 2012 - journals.plos.org
Rationale Hematopoietic stem/progenitor cells (HSPC) are responsible for maintaining the
blood system as a result of their self-renewal and multilineage differentiation capacity …
blood system as a result of their self-renewal and multilineage differentiation capacity …
Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children
S Tolani, TA Pagler, AJ Murphy, AE Bochem… - Atherosclerosis, 2013 - Elsevier
Previous studies have shown that mice with defects in cellular cholesterol efflux show
hematopoietic stem cell (HSPC) and myeloid proliferation, contributing to atherogenesis. We …
hematopoietic stem cell (HSPC) and myeloid proliferation, contributing to atherogenesis. We …
[HTML][HTML] Hypercholesterolemia tunes hematopoietic stem/progenitor cells for inflammation and atherosclerosis
X Ma, Y Feng - International Journal of Molecular Sciences, 2016 - mdpi.com
As the pathological basis of cardiovascular disease (CVD), atherosclerosis is featured as a
chronic inflammation. Hypercholesterolemia is an independent risk factor for CVD …
chronic inflammation. Hypercholesterolemia is an independent risk factor for CVD …
Hypercholesterolemia‐induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis
T Seijkens, MA Hoeksema, L Beckers… - The FASEB …, 2014 - Wiley Online Library
Modulation of hematopoietic stem and progenitor cells (HSPCs) determines immune cell
function. In this study, we investigated how hypercholesterolemia affects HSPC biology and …
function. In this study, we investigated how hypercholesterolemia affects HSPC biology and …
[HTML][HTML] LDL cholesterol modulates human CD34+ HSPCs through effects on proliferation and the IL-17 G-CSF axis
Background Hypercholesterolemia plays a critical role in atherosclerosis. CD34+ CD45dim
Lineage-hematopoietic stem/progenitor cells (HSPCs) give rise to the inflammatory cells …
Lineage-hematopoietic stem/progenitor cells (HSPCs) give rise to the inflammatory cells …
Cholesterol and hematopoietic stem cells: inflammatory mediators of atherosclerosis
Atherosclerosis causing heart attack and stroke is the leading cause of death in the modern
world. Therapy for end-stage atherosclerotic disease using CD34+ hematopoietic cells has …
world. Therapy for end-stage atherosclerotic disease using CD34+ hematopoietic cells has …
High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis
OBJECTIVE: Endothelial progenitor cells (EPCs) are implicated as an important marker of
endothelial function and cardiovascular risk. In the present study, we examined whether …
endothelial function and cardiovascular risk. In the present study, we examined whether …
The role of monocytosis and neutrophilia in atherosclerosis
DA Chistiakov, AV Grechko… - Journal of cellular …, 2018 - Wiley Online Library
Monocytosis and neutrophilia are frequent events in atherosclerosis. These phenomena
arise from the increased proliferation of hematopoietic stem and multipotential progenitor …
arise from the increased proliferation of hematopoietic stem and multipotential progenitor …
Hypercholesterolemia links hematopoiesis with atherosclerosis
O Soehnlein, FK Swirski - Trends in Endocrinology & Metabolism, 2013 - cell.com
Atherosclerosis is characterized by the progressive accumulation of lipids and leukocytes in
the arterial wall. Leukocytes such as macrophages accumulate oxidized lipoproteins in the …
the arterial wall. Leukocytes such as macrophages accumulate oxidized lipoproteins in the …
Interleukin-3/granulocyte macrophage colony–stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with …
M Wang, M Subramanian, S Abramowicz… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Coronary heart disease is associated with monocytosis. Studies using animal
models of monocytosis and atherosclerosis such as ApoE−/− mice have shown bone …
models of monocytosis and atherosclerosis such as ApoE−/− mice have shown bone …