Efficacious and clinically relevant conditioned medium of human adipose-derived stem cells for therapeutic angiogenesis

SH Bhang, S Lee, JY Shin, TJ Lee, HK Jang, BS Kim - Molecular Therapy, 2014 - cell.com
Using stem cell–conditioned medium (CM) might be a viable alternative to stem cell
transplantation, which is often hampered by low grafting efficiency and potential …

[HTML][HTML] Autologous adipose tissue as a new source of progenitor cells for therapeutic angiogenesis

T Murohara - Journal of cardiology, 2009 - Elsevier
Therapeutic angiogenesis is an important means for salvaging tissues from severe ischemic
diseases in patients with no option for other vascular interventions. A number of recent …

Adipose-Derived Stem Cells Promote Angiogenesis and Tissue Formation for In Vivo Tissue Engineering

K Matsuda, KJ Falkenberg, AA Woods… - … Engineering Part A, 2013 - liebertpub.com
Adult mesenchymal stem cells secrete a variety of angiogenic cytokines and growth factors,
so we proposed that these paracrine mechanisms may be used to promote vascularization …

Therapeutic potential of adipose-derived stem cells in vascular growth and tissue repair

SJ Hong, DO Traktuev, KL March - Current opinion in organ …, 2010 - journals.lww.com
ASCs may ultimately represent a valuable therapeutic option in tissue rescue and repair
based on their ready availability, proangiogenesis and antiapoptotic factor secretion …

Adipose stromal cells stimulate angiogenesis via promoting progenitor cell differentiation, secretion of angiogenic factors, and enhancing vessel maturation

K Rubina, N Kalinina, A Efimenko… - … Engineering Part A, 2009 - liebertpub.com
Adipose-derived stromal cells (ASCs) are suggested to be potent candidates for cell therapy
of ischemic conditions due to their ability to stimulate blood vessel growth. ASCs produce …

The proliferation and differentiation of adipose-derived stem cells in neovascularization and angiogenesis

G Hutchings, K Janowicz, L Moncrieff… - International journal of …, 2020 - mdpi.com
Neovascularization and angiogenesis are vital processes in the repair of damaged tissue,
creating new blood vessel networks and increasing oxygen and nutrient supply for …

Locally delivered growth factor enhances the angiogenic efficacy of adipose-derived stromal cells transplanted to ischemic limbs

SH Bhang, SW Cho, JM Lim, JM Kang, TJ Lee… - Stem …, 2009 - academic.oup.com
Ischemia is a potentially fatal medical event that is associated with as many as 30% of all
deaths. Stem cell therapy offers significant therapeutic promise, but poor survival following …

Direct comparison of human mesenchymal stem cells derived from adipose tissues and bone marrow in mediating neovascularization in response to vascular …

YJ Kim, HK Kim, HH Cho, YC Bae, KT Suh… - Cellular Physiology and …, 2007 - karger.com
Abstract Background/Aim: Although transplantation of MSC derived from bone marrow or
adipose tissues has been shown in proangiogenic action in hindlimb ischemia model of …

Concise review: therapeutic potential of adipose tissue-derived angiogenic cells

K Szöke, JE Brinchmann - Stem Cells Translational Medicine, 2012 - academic.oup.com
Inadequate blood supply to tissues is a leading cause of morbidity and mortality today.
Ischemic symptoms caused by obstruction of arterioles and capillaries are currently not …

Preconditioning by mitochondrial reactive oxygen species improves the proangiogenic potential of adipose-derived cells-based therapy

A Carrière, TG Ebrahimian, S Dehez… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Transplantation of adipose-derived stroma cells (ADSCs) stimulates
neovascularization after experimental ischemic injury. ADSC proangiogenic potential is …