Atherosclerosis.

P Libby, JE Buring, L Badimon… - Nature reviews …, 2019 - europepmc.org
Atherosclerosis, the formation of fibrofatty lesions in the artery wall, causes much morbidity
and mortality worldwide, including most myocardial infarctions and many strokes, as well as …

Atherogenesis: current understanding of the causes of atheroma

PL Weissberg - Heart, 2000 - heart.bmj.com
Accumulated subendothelial lipid, particularly if oxidised, exacerbates the local inflammatory
reaction and maintains activation of the overlying endothelium. This results in continued …

Pathogenesis of atherosclerosis

T Wang, J Butany - Diagnostic histopathology, 2017 - Elsevier
The pathogenesis of atherosclerosis involves a complex interplay of endothelial dysfunction,
lipid accumulation, inflammation, vascular smooth muscle cell proliferation, matrix turnover …

Vascular biology of atherosclerosis: overview and state of the art

P Libby - The American journal of cardiology, 2003 - Elsevier
Our current understanding of the vascular biology of atherogenesis and its clinical
manifestations suggests a pathophysiology that is much more complex than mere lipid …

Atherosclerosis: Known and unknown

J Fan, T Watanabe - Pathology international, 2022 - Wiley Online Library
Atherosclerotic disease, such as myocardial infarction and stroke, is the number one killer
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …

Pathogenesis of atherosclerosis

MA Crowther - ASH Education Program Book, 2005 - ashpublications.org
Atherosclerosis is no longer considered a disorder due to abnormalities in lipid metabolism.
In fact, the inciting event of atherosclerosis is likely an inflammatory insult that occurs …

Pathogenesis of atherosclerosis

E Falk - Journal of the American College of cardiology, 2006 - jacc.org
Atherosclerosis is a multifocal, smoldering, immunoinflammatory disease of medium-sized
and large arteries fuelled by lipids. Endothelial cells, leukocytes, and intimal smooth muscle …

[HTML][HTML] Atherosclerosis: from lesion formation to plaque activation and endothelial dysfunction

JF Keaney Jr - Molecular aspects of medicine, 2000 - Elsevier
Atherosclerosis is an important source of morbidity and mortality in the developed world.
Despite the fact that the association between LDL cholesterol and atherosclerosis has been …

Atherosclerosis: pathogenesis and pathology

T Wang, D Palucci, K Law, B Yanagawa, J Yam… - Diagnostic …, 2012 - Elsevier
Atherosclerosis and its clinical sequelae represent a huge and increasing global burden of
morbidity and mortality in the form of coronary artery, peripheral vascular and cerebral …

Molecular biology of atherosclerosis

P Libby, G Sukhova, RT Lee, JK Liao - International journal of cardiology, 1997 - Elsevier
For much of the last century, the development of arteriosclerosis was regarded as an
inevitable degenerative process. Osler stated:“the stability of tubing of any sort depends on …