Synthesis of oligonucleotides containing N, N-disubstituted 3-deazacytosine nucleobases by post-elongation modification and their triplex-forming ability with double …

M Akabane-Nakata, S Obika, Y Hari - Organic & Biomolecular …, 2014 - pubs.rsc.org
A phosphoramidite of a 2′-O, 4′-C-methylene-bridged nucleoside, bearing 4-(2, 4, 6-
triisopropylbenzenesulfonyloxy) pyridin-2-one as a nucleobase precursor, was synthesized …

Modified oligonucleotides with triple-helix stabilization properties

R Eritja, E Ferrer, RG García… - Nucleosides & nucleotides, 1999 - Taylor & Francis
Modified Oligonucleotides with Triple-Helix Stabilization Properties Page 1 NUCLEOSIDES &
NLJCLEOTIDES, 18(6&7), 1619-1621 (1999) MODIFIED OLIGONUCLEOTIDES WITH …

Synthesis of 3 '-3 '-Linked Oligonucleotides Branched by a Pentaerythritol Linker and the Thermal Stabilities of the Triplexes with Single-Stranded DNA or RNA

Y Ueno, A Shibata, A Matsuda, Y Kitade - Bioconjugate chemistry, 2003 - ACS Publications
Synthesis of 3 '-3 '-linked oligonucleotides branched by a pentaerythritol linker is described.
The branched oligonucleotides were synthesized on a DNA/RNA synthesizer using a …

Incorporation of a novel nucleobase allows stable oligonucleotide-directed triple helix formation at the target sequence containing a purine· pyrimidine interruption

D Guianvarc'h, R Benhida, JL Fourrey… - Chemical …, 2001 - pubs.rsc.org
Incorporation of a novel nucleobase allows stable oligonucleotide-directed triple helix formation at
the target sequence containing a purine·pyrimidi ... - Chemical Communications (RSC Publishing) …

Synthesis of 2′-O, 3′-C-linked bicyclic nucleosides and bicyclic oligonucleotides

P Nielsen, HM Pfundheller, CE Olsen… - Journal of the Chemical …, 1997 - pubs.rsc.org
The 3′-C-allyl furanose 4 has been used as a precursor for synthesis of the novel 2′-O,
3′-C-linked bicyclic thymine nucleosides 15, 16, 20 and 25. The three bicyclic β …

Synthesis and triplex forming properties of pyrrolidino pseudoisocytidine containing oligodeoxynucleotides

A Mayer, A Häberli, CJ Leumann - Organic & biomolecular chemistry, 2005 - pubs.rsc.org
Pyrrolidino pseudo-C-nucleosides are isosteres of natural deoxynucleosides which are
protonated at the pyrrolidino ring nitrogen under physiological conditions. As constituents of …

Properties of triple helix formation with oligodeoxyribonucleotides containing 8-oxo-2′-deoxyadenosine and 2′-modified nucleoside derivatives

T Ishibashi, H Yamakawa, Q Wang, S Tsukahara… - Bioorganic & Medicinal …, 1996 - Elsevier
The ability of homopyrimidine oligonucleotides containing 8-oxo-2′-deoxyadenosine
(dAOH), 2′-methoxyuridine (Um). 2′-fluorouridine (Uf), 2′-methoxycytidine (Cm), and …

2′, 4′-BNA derivatives bearing an unnatural nucleobase: Synthesis and application to triplex-forming oligonucleotides

H Inohara, S Obika, T Imanishi - Nucleic Acids Symposium …, 2004 - academic.oup.com
Recognition of dsDNA by a triplex-forming oligonucleotide (TFO) is limited to homopurine·
homopyrimidine sequences. Therefore, it is necessary to develop novel nucleoside …

5′-5′ Tethered oligonucleotides via nucleic bases: a potential new set of compounds for alternate strand triple-helix formation

U Asseline, NT Thuong - Tetrahedron letters, 1994 - Elsevier
The solid-phase synthesis of 5′-5′-linked oligonucleotides tethered via nucleic bases and
with opposite polarities has been performed using a modified dinucleoside bearing a …

Triple‐Helix Formation by Pyrimidine Oligonucleotides Containing Nonnatural Nucleosides with Extended Aromatic Nucleobases: Intercalation from the major groove …

TE Lehmann, WA Greenberg, DA Liberles… - Helvetica Chimica …, 1997 - Wiley Online Library
The sequence‐specific recognition of double‐helical DNA by oligonucleotide‐directed triple
helix formation is limited primarily to purine tracts. To identify potential lead compounds …