[HTML][HTML] Linalool prevents cisplatin induced muscle atrophy by regulating IGF-1/Akt/FoxO pathway

H Zhang, M Chi, L Chen, X Sun, L Wan… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle atrophy is an important feature of cancer cachexia, which can be induced by
chemotherapy, and affects the survival and quality of life of cancer patients seriously. No …

[HTML][HTML] Naringenin alleviates cisplatin induced muscle atrophy by regulating RIPK1/AMPK/NF-κB pathway

H Zhang, M Chi, Y Wang, L Chen, X Sun, L Wan… - Journal of Functional …, 2021 - Elsevier
Cisplatin (DDP) is a commonly used chemotherapy drug, but DDP can cause skeletal
muscle atrophy and cachexia. This study combined the DDP-induced C2C12 myotube …

Silibinin alleviates muscle atrophy caused by oxidative stress induced by cisplatin through ERK/FoxO and JNK/FoxO pathways

M Chi, H Zhang, Y Wang, X Sun… - … Medicine and Cellular …, 2022 - Wiley Online Library
Cisplatin (DDP), a widely used chemotherapeutic drug in cancer treatment, causes oxidative
stress, resulting in cancer cachexia and skeletal muscle atrophy. This study investigated the …

Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling

X Chen, Y Wu, T Yang, M Wei, Y Wang… - Journal of cachexia …, 2016 - Wiley Online Library
Background Cachexia has a devastating impact on survival and quality of life for many
cancer patients and contributes to nearly one‐third of all cancer deaths; also, it is associated …

Screening of phytochemicals effective on relieving cancer cachexia in cisplatin-induced in vitro sarcopenia model

C Lee, MJ Kang, S Kim, IH Han, H Bae - Molecular & Cellular Toxicology, 2022 - Springer
Background Cancer cachexia is a lethal metabolic syndrome induced by cancer and
chemotherapy administration and characterized by marked muscle wasting. Although …

[HTML][HTML] Supplementation of magnolol attenuates skeletal muscle atrophy in bladder cancer-bearing mice undergoing chemotherapy via suppression of FoxO3 …

MC Chen, YL Chen, CF Lee, CH Hung, TC Chou - PloS one, 2015 - journals.plos.org
Skeletal muscle atrophy, the most prominent phenotypic feature of cancer cachexia, is often
observed in cancer patients undergoing chemotherapy. Magnolol (M) extracted from …

Daidzein alleviates cisplatin‐induced muscle atrophy by regulating Glut4/AMPK/FoxO pathway

H Zhang, M Chi, L Chen, X Sun, L Wan… - Phytotherapy …, 2021 - Wiley Online Library
Cisplatin (DDP) is widely used in cancer treatment, but DDP can cause skeletal muscle
atrophy and cachexia. This study explored the effect and mechanism of daidzein (DAI) in …

Alantolactone ameliorates cancer cachexia-associated muscle atrophy mainly by inhibiting the STAT3 signaling pathway

Q Shen, JX Kuang, CX Miao, WL Zhang, YW Li… - Phytomedicine, 2022 - Elsevier
Background Cancer cachexia is a serious metabolic disorder syndrome that is responsible
for the deaths of approximately 30% of patients with cancer, but effective drugs for cancer …

Carboxyamidotriazole alleviates muscle atrophy in tumor-bearing mice by inhibiting NF-κB and activating SIRT1

C Chen, R Ju, L Zhu, J Li, W Chen, D Zhang… - Naunyn-Schmiedeberg's …, 2017 - Springer
Cancer cachexia is a complex disorder characterized by inflammatory responses, and it is
associated with poor performance status and high mortality rate of cancer patients …

Corylifol A ameliorates muscle atrophy by inhibiting TAOK1/p38‐MAPK/FoxO3 pathway in cancer cachexia

R Zhang, Q Shen, Y Wang, X Deng… - Journal of Cachexia …, 2023 - Wiley Online Library
Abstract Background Corylifol A (CYA) is one of the main active components of Psoralea
corylifolia L. CYA had been reported to have ameliorating effects on dexamethasone …