Platelet activation plays an important role in the development of sepsis. During sepsis,
platelet activation leads to endothelial cell injury and promotes neutrophil extracellular trap …

Purpose Abnormal platelet activation plays an important role in the development of sepsis.
The effect of antiplatelet drugs on the outcome of patients with sepsis remains unclear. This …

As mechanisms of sepsis pathophysiology have been elucidated with time, sepsis may be
considered nowadays, as an uncontrolled inflammatory and pro-coagulant response to a …

Sepsis is accompanied by thrombocytopenia and the severity of the thrombocytopenia is
associated with mortality. This thrombocytopenia is characteristic of disseminated …

Platelet activation has been implicated in microvascular thrombosis and organ failure in
critically ill patients. In the first part the present paper summarises important data on the role …

Objective: Sepsis, a serious and life threatening complication arising from infection caused
by lipopolysaccharide, is a complex inflammatory syndrome, and one of the main causes of …

A State of the Art lecture titled “The role of platelets in sepsis” was presented at the ISTH
congress in 2020. Sepsis is a life‐threatening organ dysfunction caused by a dysregulated …

Conclusions Platelets play a complex role in sepsis; they are able to modulate not only their
own function but also that of cells around them. Further study is needed to better define the …

Sepsis is a common condition that is associated with significant morbidity, mortality and
health-care cost. Pulmonary and non-pulmonary sepsis are common causes of the acute …

Purpose Sepsis is a major health burden worldwide. Preclinical investigations in animals
and retrospective studies in patients have suggested that inhibition of platelets may improve …