Challenges in mass spectrometry based targeted metabolomics

T Koal, HP Deigner - Current molecular medicine, 2010 - ingentaconnect.com
The gap of the post-genomic era is increasingly being filled by the metabolomics approach,
comprising a technology for analyzing small molecule endogenous metabolites (≤ 1500 …

From targeted quantification to untargeted metabolomics

V Lelli, A Belardo, AM Timperio - … Methodology and Applications …, 2021 - books.google.com
Metabolomics is an emerging and rapidly evolving technology tool, which involves
quantitative and qualitative metabolite assessments science. It offers tremendous promise …

Analytical methods for mass spectrometry-based metabolomics studies

S Wang, IA Blair, C Mesaros - Advancements of Mass Spectrometry in …, 2019 - Springer
The advancement of mass spectrometry-based analytical platform largely facilitates small-
molecule metabolomics studies, which allows simultaneously analysis of a large number of …

Challenges in translating clinical metabolomics data sets from the bench to the bedside

CZ Ulmer, A Maus, J Hines, R Singh - Clinical chemistry, 2021 - academic.oup.com
Metabolomics encompasses the comprehensive study of metabolism as it pertains to a
biological system in response to a stimulus or pathophysiological condition. Lipidomics, a …

Modern analytical techniques in metabolomics analysis

A Zhang, H Sun, P Wang, Y Han, X Wang - Analyst, 2012 - pubs.rsc.org
Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

Quality assurance procedures for mass spectrometry untargeted metabolomics. a review

D Dudzik, C Barbas-Bernardos, A García… - … of pharmaceutical and …, 2018 - Elsevier
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …

[HTML][HTML] Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

FA Castelli, G Rosati, C Moguet, C Fuentes… - Analytical and …, 2022 - Springer
Metabolomics refers to the large-scale detection, quantification, and analysis of small
molecules (metabolites) in biological media. Although metabolomics, alone or combined …

Novel methodologies in metabolic profiling with a focus on molecular diagnostic applications

T Hyötyläinen - Expert Review of Molecular Diagnostics, 2012 - Taylor & Francis
The metabolome contains all the biological end points of genomic, transcriptomic and
proteomic perturbations, also including the influence of gut microbiota and the environment …

Metabolomics toward personalized medicine

M Jacob, AL Lopata, M Dasouki… - Mass spectrometry …, 2019 - Wiley Online Library
Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …

Metabolomics analysis for biomarker discovery: advances and challenges

MS Monteiro, M Carvalho, ML Bastos… - Current medicinal …, 2013 - ingentaconnect.com
Over the last decades there has been a change in biomedical research with the search for
single genes, transcripts, proteins, or metabolites being substituted by the coverage of the …