Abstract Study Type-Aetiology (cohort) Level of Evidence 2b OBJECTIVE• To describe
clinical and histopathological characteristics of Finnish familial prostate cancer (PCa) …

PURPOSE: A family history of prostate cancer is an important risk factor for this disease. The
clinical presentation and prognosis of familial disease remain uncertain. In this study these …

BACKGROUND Although prostate carcinoma is not widely recognized as a familial cancer,
familial aggregation of this disease has been shown in some retrospective case–control …

Background In view of demographic changes and previous research results, it is debatable
whether hereditary criteria should be further applied when it comes to determining the status …

Epidemiologic studies have shown that hereditary forms account for approximately 10% of
all prostate cancers. The identification of several susceptibility loci harboring predisposing …

Prostate cancer is the second most common malignant tumor in German males with 28,000
new cases diagnosed every year. One of the strongest risk factors is a family history for the …

Prostate cancer is a pervasive disease in the USA, with about 244000 cases diagnosed in
1995 [1]. It is the most commonly diagnosed cancer in men and the second most common …

Objectives To compare traditional prognostic characteristics of familial vs sporadic prostate
cancers and to investigate potential detection biases arising from differences in the use of …

Prostate cancer is a significant public health problem. There are about 14000 cases per year
in England and Wales, and 10000 deaths [J]. In the USA, it is the most common malignancy …

Background: Clinical features of familial prostate cancer (PCa) and other malignancies
associated with PCa are poorly described. Using a large family-based data registry of …