Sex differences in muscle wasting

LJ Anderson, H Liu, JM Garcia - Sex and gender factors affecting …, 2017 - Springer
With aging and other muscle wasting diseases, men and women undergo similar
pathological changes in skeletal muscle: increased inflammation, enhanced oxidative …

Muscle metabolism and atrophy: let's talk about sex

ME Rosa-Caldwell, NP Greene - Biology of sex differences, 2019 - Springer
Skeletal muscle health is a strong predictor of overall health and longevity. Pathologies
affecting skeletal muscle such as cancer cachexia, intensive care unit treatment, muscular …

Aging of the musculoskeletal system: How the loss of estrogen impacts muscle strength

BC Collins, EK Laakkonen, DA Lowe - Bone, 2019 - Elsevier
Skeletal muscle weakness occurs with aging and in females this is compounded by the loss
of estrogen with ovarian failure. Estrogen deficiency mediates decrements in muscle …

Sex hormones and skeletal muscle weakness

S Sipilä, M Narici, M Kjaer, E Pöllänen, RA Atkinson… - Biogerontology, 2013 - Springer
Human ageing is accompanied with deterioration in endocrine functions the most notable
and well characterized of which being the decrease in the production of sex hormones …

Mechanisms of estrogen influence on skeletal muscle: mass, regeneration, and mitochondrial function

A Pellegrino, PM Tiidus, R Vandenboom - Sports medicine, 2022 - Springer
Human menopause is widely associated with impaired skeletal muscle quality and
significant metabolic dysfunction. These observations pose significant challenges to the …

The role of hormones, cytokines and heat shock proteins during age-related muscle loss

CE Lee, A McArdle, RD Griffiths - Clinical Nutrition, 2007 - Elsevier
Ageing is associated with a progressive decline of muscle mass, strength, and quality, a
condition known as sarcopenia. Due to the progressive ageing of western populations, age …

Sex differences in inflammation and muscle wasting in aging and disease

C Della Peruta, B Lozanoska-Ochser… - International journal of …, 2023 - mdpi.com
Only in recent years, thanks to a precision medicine-based approach, have treatments
tailored to the sex of each patient emerged in clinical trials. In this regard, both striated …

Differential influence of peripheral and systemic sex steroids on skeletal muscle quality in pre‐and postmenopausal women

E Pöllänen, S Sipilä, M Alen, PHA Ronkainen… - Aging cell, 2011 - Wiley Online Library
Aging is associated with gradual decline of skeletal muscle strength and mass often leading
to diminished muscle quality. This phenomenon is known as sarcopenia and affects about …

Understanding age-related changes in skeletal muscle metabolism: differences between females and males

BJF Gheller, ES Riddle, MR Lem… - Annual review of …, 2016 - annualreviews.org
Skeletal muscle is the largest metabolic organ system in the human body. As such,
metabolic dysfunction occurring in skeletal muscle impacts whole-body nutrient …

Sarcopenia, cachexia and aging: diagnosis, mechanisms and therapeutic options-a mini-review

S Ali, JM Garcia - Gerontology, 2014 - karger.com
By the year 2050, individuals over the age of 65 years will comprise 20% of the US
population. Loss of muscle mass and strength is common in this age group and it is …