The inclusion of plasma levels of the natural amino acids plus 2.5 mM glutamate and 2.5 mM
malate (PAAGM) raised the oxygen consumption and glucose oxidation of isolated cardiac …

METHODS Albino rabbits of both sexes, 6-8 weeks old, were maintained under standard
conditions and allowed free access to food and water. Hearts were quickly removed from …

Protein synthesis in heart muscle has been studied in the isolated rat heart perfused with
buffer containing glucose and various amino acid mixtures. The rate of synthesis was …

In oxygen-deprived heart muscle tissue, alanine levels increase, whereas levels of
glutamate and aspartate decline, and it is therefore postulated that free tissue amino acids …

1. The influx of nineteen amino acids into the heart of the living rat was studied by a method
specially devised for experiments under controlled conditions in vivo. 2. When, in separate …

MATERIALS AND METHODS L-Alanine dehydrogenase(EC 1.4. 1.1.), L-glutamate
dehydrogenase (EC 1.4. 1.3.), and beef heart L-lactate dehydrogenase(EC 1.1. 1.27). as a …

The metabolism and intracellular compartmentalization of adenine nucleotides in a
preparation of adult rat heart myocytes showing good morphology, viability, and tolerance to …

Perfusion of the isolated rat heart under anaerobic conditions inhibited synthesis of whole
heart protein and myosin. The effect was reversible and did not appear to be due to the …

By measuring the absorbance change due to myoglobin oxygenation in hemoglobin-free
isolated perfused rat hearts, we analyzed effects of perfusion pressure and heart rate upon …

METHODS Heart perfusion. Male Sprague-Dawley rats (250-300 g) were fasted overnight
and injected with sodium heparin (2.5 mg) 30 min prior to death. Following intraperitoneal …