Angiogenesis and vascular remodeling support fibroproliferative processes; however, no
study has addressed the importance of angiogenesis during fibro-obliteration of the allograft …

Bronchiolitis obliterans syndrome (BOS) is the major limitation to survival post-lung
transplantation and is characterized by a persistent peribronchiolar inflammation that …

Lung transplantation remains the only effective therapy for patients with end-stage lung
disease, but survival is limited by the development of obliterative bronchiolitis (OB). The …

Bronchiolitis obliterans syndrome (BOS) is the major limitation to survival after lung
transplantation. Acute rejection, its main risk factor, is characterized by perivascular …

Small airway fibrosis (bronchiolitis obliterans syndrome) is the primary obstacle to long-term
survival following lung transplantation. Here, we show the importance of functional …

The role of complement activation in the development of obliterative bronchiolitis, a
manifestation of chronic lung allograft rejection, was investigated in the heterotopic rat …

Lung transplantation is a therapeutic option for a number of end-stage pulmonary disorders.
Early lung allograft dysfunction (ischemia-reperfusion injury) continues to be the most …

Acute allograft rejection is a major complication postlung transplantation and is the main risk
factor for the development of bronchiolitis obliterans syndrome. Acute rejection is …

Outcomes following lung transplant are suboptimal owing to chronic allograft failure termed
bronchiolitis obliterans syndrome (BOS). Prior work in both mice and humans has shown …

Although lung transplantation is a widely applied therapeutic modality for end-stage
pulmonary disease, the long-term survival following this procedure is limited by the …