[HTML][HTML] Predictive biomarkers for anti-TNF alpha therapy in IBD patients

M Kumar, S Murugesan, N Ibrahim, M Elawad… - Journal of Translational …, 2024 - Springer
Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition characterized by
severe gut inflammation, commonly presenting as Crohn's disease, ulcerative colitis or …

[HTML][HTML] Evaluation of anti-TNF therapeutic response in patients with inflammatory bowel disease: Current and novel biomarkers

G Cui, Q Fan, Z Li, R Goll, J Florholmen - EBioMedicine, 2021 - thelancet.com
Neutralizing tumour necrosis factor (TNF) antibodies have been widely used to treat
inflammatory bowel disease (IBD) in the clinical practice. In this review, the principal …

[HTML][HTML] Personalizing treatment in IBD: hype or reality in 2020? Can we predict response to anti-TNF?

R Atreya, MF Neurath, B Siegmund - Frontiers in medicine, 2020 - frontiersin.org
The advent of anti-TNF agents as the first approved targeted therapy in the treatment of
inflammatory bowel disease (IBD) patients has made a major impact on our existing …

[HTML][HTML] Can we predict the efficacy of anti-TNF-α agents?

LR Lopetuso, V Gerardi, V Papa, F Scaldaferri… - International journal of …, 2017 - mdpi.com
The use of biologic agents, particularly anti-tumor necrosis factor (TNF)-α, has revolutionized
the treatment of inflammatory bowel diseases (IBD), modifying their natural history. Several …

Exploring the role of monitoring anti-TNFα drug and antibody levels in the management of inflammatory bowel disease

AW Lim, R Panaccione… - Therapeutic Advances in …, 2011 - journals.sagepub.com
Crohn's disease and ulcerative colitis are chronic inflammatory gastrointestinal disorders
which often result in significant morbidity or surgery. Current treatment options are not …

Approach to optimize anti-TNF-α therapy in patients with IBD

Y Komaki, F Komaki, A Sakuraba, R Cohen - Current treatment options in …, 2016 - Springer
Opinion statement Tumor necrosis factor-α (TNF-α) is an inflammatory cytokine that plays a
major role during the initiation and perpetuation of inflammatory bowel disease (IBD). Anti …

How to predict response to anti-tumour necrosis factor agents in inflammatory bowel disease

S Naviglio, P Giuffrida, G Stocco, MV Lenti… - Expert review of …, 2018 - Taylor & Francis
Introduction: Anti-tumor necrosis factor (TNF) agents have changed the therapeutic
approach to inflammatory bowel disease (IBD). However, a considerable proportion of …

Considerations, challenges and future of anti-TNF therapy in treating inflammatory bowel disease

L Pouillon, P Bossuyt… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Crohn's disease (CD) and ulcerative colitis (UC) are chronic disabling
conditions. Monoclonal antibody therapy directed against tumor necrosis factor-alpha (anti …

[HTML][HTML] Treatment patterns and intensification within 5 year of follow-up of the first-line anti-TNFα used for the treatment of IBD: Results from the VERNE study

G Bastida, I Marín-Jiménez, A Forés… - Digestive and Liver …, 2022 - Elsevier
Background Anti-TNFα represent one of the main treatment approaches for the management
of inflammatory bowel diseases (IBD). Therefore, the evaluation of their treatment patterns …

[HTML][HTML] Clinical and laboratory markers associated with anti-TNF-alpha trough levels and anti-drug antibodies in patients with inflammatory bowel diseases

AB Grinman, C Maria das Graças, E Bouskela… - Medicine, 2020 - journals.lww.com
Monitoring anti-TNF agents in inflammatory bowel disease (IBD) patients may be helpful in
optimizing outcomes. We aimed to evaluate potential correlations among demographic …