Multifunctional nanozyme hydrogel with mucosal healing activity for single-dose ulcerative colitis therapy
Nanozymes are nanomaterials with enzyme-like activities, which have been developed for
inflammatory disease therapy by reactive oxygen species (ROS) scavenging. The …
inflammatory disease therapy by reactive oxygen species (ROS) scavenging. The …
Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …
N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
[HTML][HTML] Oral administration of therapeutic enzyme capsule for the management of inflammatory bowel disease
X Liang, K Wen, Y Chen, G Fang… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Background Oral administration of proteins/peptides is challenging in clinical application
due to their instability and susceptibility in the gastrointestinal tract. Materials and Methods …
due to their instability and susceptibility in the gastrointestinal tract. Materials and Methods …
Oral nanozyme-engineered probiotics for the treatment of ulcerative colitis
H Zhao, Y Du, L Liu, Y Du, K Cui, P Yu, L Li… - Journal of Materials …, 2022 - pubs.rsc.org
Probiotic-based therapy for ulcerative colitis (UC) is a novel and promising approach that
has gained much popularity in recent years. However, probiotics may be easily captured …
has gained much popularity in recent years. However, probiotics may be easily captured …
[HTML][HTML] A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
[HTML][HTML] Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease
Y Cao, K Cheng, M Yang, Z Deng, Y Ma, X Yan… - Journal of …, 2023 - Springer
Background Inflammatory bowel disease (IBD) is a chronic nonspecific disease with
unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a …
unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a …
Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy
Here, an integrated cascade nanozyme with a formulation of Pt@ PCN222-Mn is developed
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …
Hyaluronic acid/serotonin-decorated cerium dioxide nanomedicine for targeted treatment of ulcerative colitis
Y Gao, J Zou, B Chen, Y Cao, D Hu, Y Zhang… - Biomaterials …, 2023 - pubs.rsc.org
Ulcerative colitis (UC) is a chronic nonspecific inflammatory bowel disease often
characterized by rapid progression and frequent comorbidities that make its treatment …
characterized by rapid progression and frequent comorbidities that make its treatment …
Biomimetic MOF nanoparticles delivery of C-dot nanozyme and CRISPR/Cas9 system for site-specific treatment of ulcerative colitis
Y Ma, W Gao, Y Zhang, M Yang, X Yan… - … Applied Materials & …, 2022 - ACS Publications
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) of unknown etiology
affecting the colon and rectum. Previous studies have found that reactive oxygen species …
affecting the colon and rectum. Previous studies have found that reactive oxygen species …
Salen-manganese complex-based nanozyme with enhanced superoxide-and catalase-like activity for wound disinfection and anti-inflammation
X Dai, Q Xu, Y Li, L Yang, Y Zhang, X Liu… - Chemical Engineering …, 2023 - Elsevier
Skin wound healing remains a key challenge owing to its vulnerability to pathogen infection,
oxidative stress and persistent inflammatory response. Herein, a salen-manganese complex …
oxidative stress and persistent inflammatory response. Herein, a salen-manganese complex …
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