Squamous cell carcinoma of the head and neck (SCCHN) presents at a locally advanced
(LA) stage in many patients. Chemotherapy, which is one fundamental therapy mode for …

Background Concurrent chemoradiotherapy (CCRT) is the standard treatment for patients
with unresectable, nonmetastatic locoregionally advanced squamous-cell carcinoma of the …

Background Phase 3 studies suggest that induction chemotherapy (ICT) of cisplatin and 5-
fluorouracil plus docetaxel (TPF) is effective but toxic for patients with squamous-cell …

Opinion statement Induction chemotherapy for squamous cell carcinoma of the head and
neck has long been known to be highly active with tumor responses observed in a high …

The use of induction chemotherapy prior to chemoradiation for locally advanced head and
neck squamous cell carcinoma (LA-HNSCC) remains controversial. We explored whether …

Background The purpose of this phase II trial was to evaluate the tolerability, safety, and
efficacy of a non–5‐fluorouracil (5‐FU)‐based induction chemotherapy followed by …

Head and neck cancers are a complex group of diseases defined by variations in
histological features, anatomical location, and cause. Once the realm of surgeons and …

Background: Head and Neck Cancer is a major public health problem in India, majority of
which are lifestyle related, male predominant requiring dedicated infrastructure and human …

Abstract Treatment options of patients with advanced head and neck cancer developed in
the last years. Surgical approaches with or without radiotherapy used to be the standard …

Background The role of induction chemotherapy in advanced squamous cell carcinoma of
the head and neck (SCCHN) is under constant debate. Surgery, radiotherapy …