METTL3 stabilization by PIN1 promotes breast tumorigenesis via enhanced m6A-dependent translation
PY Bhattarai, G Kim, SC Lim, R Mariappan, T Ohn… - Oncogene, 2023 - nature.com
Abstract Methyltransferase-like 3 (METTL3) is the catalytic subunit of the N 6-adenosine
methyltransferase complex responsible for N 6-methyladenosine (m6A) modification of …
methyltransferase complex responsible for N 6-methyladenosine (m6A) modification of …
[HTML][HTML] Dynamics of TET family expression in porcine preimplantation embryos is related to zygotic genome activation and required for the maintenance of NANOG
K Lee, J Hamm, K Whitworth, L Spate, K Park… - Developmental …, 2014 - Elsevier
Dynamic changes in DNA methylation are observed during embryo development. Recent
studies show that the TET family is involved in these changes by converting 5 …
studies show that the TET family is involved in these changes by converting 5 …
[HTML][HTML] m6A Methylases Regulate Myoblast Proliferation, Apoptosis and Differentiation
X Yang, C Mei, X Ma, J Du, J Wang, L Zan - Animals, 2022 - mdpi.com
Simple Summary N 6-methyladenosine (m6A) is the most prevalent methylation modification
in eukaryotic mRNA, and it plays an important role in regulating gene expression. Previous …
in eukaryotic mRNA, and it plays an important role in regulating gene expression. Previous …
[HTML][HTML] Cloning of the RNA m6A Methyltransferase 3 and Its Impact on the Proliferation and Differentiation of Quail Myoblasts
J Liu, W Zhang, W Luo, S Liu, H Jiang, S Liu, J Xu… - Veterinary …, 2023 - mdpi.com
Simple Summary RNA N6-methyladenosine (m6A) modification plays an important role in
RNA processing, transport, translation, and stem cell differentiation. However, the function of …
RNA processing, transport, translation, and stem cell differentiation. However, the function of …
The function of the m6A methyltransferase METTL3 in goat early embryo development under hypoxic and normoxic conditions
It has been reported that N6-methyladenosine (m6A) methyltransferase-like 3 (METTL3)
plays an important role in zygote genome activation during embryonic development, but the …
plays an important role in zygote genome activation during embryonic development, but the …
[HTML][HTML] Wilms' tumor 1-associating protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences
K Horiuchi, T Kawamura, T Hamakubo - Journal of Biological Chemistry, 2021 - ASBMB
Wilms' tumor 1-associating protein (WTAP) is a core component of the N6-methyladenosine
(m6A)-methyltransferase complex, along with VIRMA, CBLL1, ZC3H13 (KIAA0853) …
(m6A)-methyltransferase complex, along with VIRMA, CBLL1, ZC3H13 (KIAA0853) …
Inhibition of METTL5 improves preimplantation development of mouse somatic cell nuclear transfer embryos
L Zhang, M Yuan, X Huang, Q Cao, S Huang… - …, 2022 - rep.bioscientifica.com
In brief Several factors affect the reprogramming efficiency of nuclear transfer embryos. This
study shows that inhibiting 18S rRNA m 6 A methyltransferase METTL5 during nuclear …
study shows that inhibiting 18S rRNA m 6 A methyltransferase METTL5 during nuclear …
[HTML][HTML] The perturbed expression of m6A in parthenogenetic mouse embryos
J Hao, Y Xianfeng, W Gao, J Wei, M Qi… - … and molecular biology, 2019 - SciELO Brasil
Parthenogenetically activated oocytes cannot develop to term in mammals owing to
abnormal epigenetic modifications. Methylation of the N6 position of adenosine (m6A) is a …
abnormal epigenetic modifications. Methylation of the N6 position of adenosine (m6A) is a …
Tet3 is required for normal in vitro fertilization preimplantation embryos development of bovine
H Cheng, J Zhang, S Zhang, Y Zhai… - Molecular …, 2019 - Wiley Online Library
DNA methylation is a central epigenetic event that regulates cellular differentiation,
reprogramming, and pathogenesis. DNA demethylation occurs in preimplantation embryos …
reprogramming, and pathogenesis. DNA demethylation occurs in preimplantation embryos …
Wilms tumor 1 associated protein promotes epithelial mesenchymal transition of gastric cancer cells by accelerating TGF-β and enhances chemoradiotherapy …
Y Liu, M Da - Journal of cancer research and clinical oncology, 2023 - Springer
Purpose Wilms tumor 1 associated protein (WTAP) is a key RNA n6-methyladenosine (m6A)
methylase, which predicts the occurrence of many diseases, such as liver fibrosis formation …
methylase, which predicts the occurrence of many diseases, such as liver fibrosis formation …