[HTML][HTML] Characterization of METTL16 as a cytoplasmic RNA binding protein
DJ Nance, ER Satterwhite, B Bhaskar, S Misra… - PLoS …, 2020 - journals.plos.org
mRNA modification by N6-methyladenosine (m6A) is involved in many post-transcriptional
regulation processes including mRNA stability, splicing and promotion of translation …
regulation processes including mRNA stability, splicing and promotion of translation …
[HTML][HTML] Profiling analysis of N6-methyladenosine mRNA methylation reveals differential m6A patterns during the embryonic skeletal muscle development of ducks
B Chen, S Liu, W Zhang, T Xiong, M Zhou, X Hu, H Mao… - Animals, 2022 - mdpi.com
Simple Summary Recent studies show that N6-methyladenosine (m6A) modification, the
most common RNA chemical modification, influences the modification, processing, transport …
most common RNA chemical modification, influences the modification, processing, transport …
Neurotrophin-4 promotes the specification of trophectoderm lineage after parthenogenetic activation and enhances porcine early embryonic development
Neurotrophin-4 (NT-4), a neurotrophic factor, appears to affect early embryonic development
because it is secreted not only by neurons but also by oviductal and uterine epithelial cells …
because it is secreted not only by neurons but also by oviductal and uterine epithelial cells …
[HTML][HTML] Characterization of sexual maturity-associated N6-methyladenosine in boar testes
P Zhang, F Zhang, H Sui, X Yang, Y Ji, S Zheng, W Li… - BMC genomics, 2024 - Springer
Background The health and size of the testes are crucial for boar fertility. Testicular
development is tightly regulated by epigenetics. N6-methyladenosine (m6A) modification is …
development is tightly regulated by epigenetics. N6-methyladenosine (m6A) modification is …
[PDF][PDF] Stabilization of ERK-phosphorylated METTL3 by USP5 increases m6A methylation
Summary N 6-methyladenosine (m 6 A) is the most abundant mRNA modification and is
installed by the METTL3-METTL14-WTAP methyltransferase complex. Although the …
installed by the METTL3-METTL14-WTAP methyltransferase complex. Although the …
SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function
Y Du, G Hou, H Zhang, J Dou, J He, Y Guo… - Nucleic acids …, 2018 - academic.oup.com
Abstract The methyltransferase like 3 (METTL3) is a key component of the large N6-
adenosine-methyltransferase complex in mammalian responsible for N6-methyladenosine …
adenosine-methyltransferase complex in mammalian responsible for N6-methyladenosine …
[HTML][HTML] Effect of TET inhibitor on bovine parthenogenetic embryo development
J Zhang, S Zhang, Y Wang, H Cheng, L Hao, Y Zhai… - PLoS …, 2017 - journals.plos.org
DNA demethylation catalysed by the ten-eleven translocation (TET) protein is an important
step during extensive global epigenetic reprogramming in mammals. However, whether TET …
step during extensive global epigenetic reprogramming in mammals. However, whether TET …
[HTML][HTML] The m6A methyltransferase WTAP plays a key role in the development of diffuse large B-cell lymphoma via regulating the m6A modification of catenin beta 1
S Guo, C Zhao, L Fang, W Xu, S Dalia… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Diffuse large B-cell lymphoma (DLBCL) is the most frequently occurring
subtype of lymphoma. Unfortunately, the fundamental processes underlying the …
subtype of lymphoma. Unfortunately, the fundamental processes underlying the …
[PDF][PDF] Discovery of small molecules that activate RNA methylation through cooperative binding to the METTL3-14-WTAP complex active site
S Selberg, D Blokhina, M Aatonen, P Koivisto… - Cell reports, 2019 - cell.com
Chemical modifications of RNA provide an additional, epitranscriptomic, level of control over
cellular functions. N-6-methylated adenosines (m6As) are found in several types of RNA …
cellular functions. N-6-methylated adenosines (m6As) are found in several types of RNA …
Loss of Wtap results in cerebellar ataxia and degeneration of Purkinje cells
Y Yang, G Huang, X Jiang, X Li, K Sun, Y Shi… - Journal of Genetics and …, 2022 - Elsevier
Abstract N 6-methyladenosine (m 6 A) modification, which is achieved by the
METTL3/METTL14/WTAP methyltransferase complex, is the most abundant internal mRNA …
METTL3/METTL14/WTAP methyltransferase complex, is the most abundant internal mRNA …