Goal-oriented searching mediated by ventral hippocampus early in trial-and-error learning
S Ruediger, D Spirig, F Donato, P Caroni - Nature neuroscience, 2012 - nature.com
Most behavioral learning in biology is trial and error, but how these learning processes are
influenced by individual brain systems is poorly understood. Here we show that ventral-to …
influenced by individual brain systems is poorly understood. Here we show that ventral-to …
Hippocampal brain-network coordination during volitional exploratory behavior enhances learning
Exploratory behaviors during learning determine what is studied and when, helping to
optimize subsequent memory performance. To elucidate the cognitive and neural …
optimize subsequent memory performance. To elucidate the cognitive and neural …
The ventral hippocampus is involved in multi‐goal obstacle‐rich spatial navigation
A large body of evidence shows that the hippocampus is necessary for successful spatial
navigation. Various studies have shown anatomical and functional differences between the …
navigation. Various studies have shown anatomical and functional differences between the …
Hippocampal place-cell sequences depict future paths to remembered goals
BE Pfeiffer, DJ Foster - Nature, 2013 - nature.com
Effective navigation requires planning extended routes to remembered goal locations.
Hippocampal place cells have been proposed to have a role in navigational planning, but …
Hippocampal place cells have been proposed to have a role in navigational planning, but …
Spatial learning drives rapid goal representation in hippocampal ripples without place field accumulation or goal-oriented theta sequences
BE Pfeiffer - Journal of Neuroscience, 2022 - Soc Neuroscience
The hippocampus is critical for rapid acquisition of many forms of memory, although the
circuit-level mechanisms through which the hippocampus rapidly consolidates novel …
circuit-level mechanisms through which the hippocampus rapidly consolidates novel …
Hippocampal neural activity reflects the economy of choices during goal‐directed navigation
VL Tryon, MR Penner, SW Heide, HO King… - …, 2017 - Wiley Online Library
Distinguishing spatial contexts is likely essential for the well‐known role of the hippocampus
in episodic memory. We studied whether types of hippocampal neural organization thought …
in episodic memory. We studied whether types of hippocampal neural organization thought …
Distinct hippocampal versus frontoparietal network contributions to retrieval and memory-guided exploration
Memory can profoundly influence new learning, presumably because memory optimizes
exploration of to-be-learned material. Although hippocampus and frontoparietal networks …
exploration of to-be-learned material. Although hippocampus and frontoparietal networks …
Impaired spatial selectivity and intact phase precession in two-dimensional virtual reality
During real-world (RW) exploration, rodent hippocampal activity shows robust spatial
selectivity, which is hypothesized to be governed largely by distal visual cues, although …
selectivity, which is hypothesized to be governed largely by distal visual cues, although …
Hippocampal lesions disrupt navigation based on cognitive maps but not heading vectors
JM Pearce, ADL Roberts, M Good - Nature, 1998 - nature.com
Animals can find a hidden goal in several ways. They might use a cognitive map that
encodes information about the geometric relationship between the goal and two or more …
encodes information about the geometric relationship between the goal and two or more …
A prefrontal–thalamo–hippocampal circuit for goal-directed spatial navigation
HT Ito, SJ Zhang, MP Witter, EI Moser, MB Moser - Nature, 2015 - nature.com
Spatial navigation requires information about the relationship between current and future
positions. The activity of hippocampal neurons appears to reflect such a relationship …
positions. The activity of hippocampal neurons appears to reflect such a relationship …