When mummy and daddy get under your skin: A new look at how parenting affects children's DNA methylation, stress reactivity, and disruptive behavior
G Overbeek, N Creasey, C Wesarg… - New directions for …, 2020 - Wiley Online Library
Child maltreatment is a global phenomenon that affects the lives of millions of children.
Worldwide, as many as one in three to six children encounter physical, sexual, or emotional …
Worldwide, as many as one in three to six children encounter physical, sexual, or emotional …
DNA methylation: a mediator between parenting stress and adverse child development?
RH Mulder, J Rijlaarsdam… - Parental stress and early …, 2017 - Springer
In this chapter, we provide an overview of empirical studies evaluating the role of
epigenetics in mediating the association between parenting stress and adverse child …
epigenetics in mediating the association between parenting stress and adverse child …
DNA methylation of NR3c1 in infancy: Associations between maternal caregiving and infant sex
Caregivers play a critical role in scaffolding infant stress reactivity and regulation, but the
mechanisms by which this scaffolding occurs is unclear. Animal models strongly suggest …
mechanisms by which this scaffolding occurs is unclear. Animal models strongly suggest …
Maternal attachment insecurity, maltreatment history, and depressive symptoms are associated with broad DNA methylation signatures in infants
The early environment, including maternal characteristics, provides many cues to young
organisms that shape their long-term physical and mental health. Identifying the earliest …
organisms that shape their long-term physical and mental health. Identifying the earliest …
Methylation of exons 1D, 1F, and 1H of the glucocorticoid receptor gene promoter and exposure to adversity in preschool-aged children
Epigenetic modifications to the genome are a key mechanism involved in the biological
encoding of experience. Animal studies and a growing body of literature in humans have …
encoding of experience. Animal studies and a growing body of literature in humans have …
Dynamic stress-related epigenetic regulation of the glucocorticoid receptor gene promoter during early development: The role of child maltreatment
Epigenetics processes may play a vital role in the biological embedding of early
environmental adversity and the development of psychopathology. Accumulating evidence …
environmental adversity and the development of psychopathology. Accumulating evidence …
Epigenetics and child abuse: Modern‐day Darwinism—The miraculous ability of the human genome to adapt, and then adapt again
NB Gershon, PC High - … Journal of Medical Genetics Part C …, 2015 - Wiley Online Library
It has long been recognized that early adversity can have life‐long consequences, and the
extent to which this is true is gaining increasing attention. A growing body of literature …
extent to which this is true is gaining increasing attention. A growing body of literature …
Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood
SJ Goodman, DS Roubinov, NR Bush… - Developmental …, 2019 - Wiley Online Library
A growing body of research has documented associations between adverse childhood
environments and DNA methylation, highlighting epigenetic processes as potential …
environments and DNA methylation, highlighting epigenetic processes as potential …
Epigenetic programming by maternal behavior in the human infant
OBJECTIVES: We sought to determine if variations in maternal care alter DNA methylation in
term, healthy, 5-month-old infants. This work was based on landmark studies in animal …
term, healthy, 5-month-old infants. This work was based on landmark studies in animal …
Childhood maltreatment and stress-related psychopathology: the epigenetic memory hypothesis
PE Lutz, D Almeida, LM Fiori… - Current pharmaceutical …, 2015 - ingentaconnect.com
Childhood maltreatment (CM) is all too frequent among western societies, with an estimated
prevalence of 10 to 15%. CM associates with increased risk of several psychiatric disorders …
prevalence of 10 to 15%. CM associates with increased risk of several psychiatric disorders …