Gaseous signaling molecules in cardiovascular function: from mechanisms to clinical translation

SR Lee, B Nilius, J Han - Reviews of Physiology, Biochemistry and …, 2018 - Springer
Carbon monoxide (CO), hydrogen sulfide (H 2 S), and nitric oxide (NO) constitute
endogenous gaseous molecules produced by specific enzymes. These gases are …

[PDF][PDF] Cardiovascular effects of gasotransmitter donors

M Cebová, M Kosutova, O Pechanova - Physiological Research, 2016 - biomed.cas.cz
Gasotransmitters represent a subfamily of the endogenous gaseous signaling molecules
that include nitric oxide (NO), carbon monoxide (CO), and hydrogen sulphide (H2S). These …

A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide

DJ Lefer - Proceedings of the National Academy of …, 2007 - National Acad Sciences
Cardiovascular (CV) research has largely been focused on two endogenously produced
gaseous signaling molecules, namely, nitric oxide (NO) and carbon monoxide (CO). These …

The role of carbon monoxide as a gasotransmitter in cardiovascular and metabolic regulation

AA Untereiner, L Wu, R Wang - Gasotransmitters: physiology and …, 2012 - Springer
Carbon monoxide (CO) is produced endogenously through the oxidative catabolism of
heme by heme oxygenase (HO). First described as a putative neuronal signaling …

[HTML][HTML] Mitochondrial mechanisms by which gasotransmitters (H2S, NO and CO) protect cardiovascular system against hypoxia

I Shemarova, V Nesterov, L Emelyanova… - Frontiers in Bioscience …, 2021 - imrpress.com
Over past few years, there has been a dramatic increase in studying physiological
mechanisms of the activity of various signaling low-molecular molecules that directly or …

Clinical applications for gasotransmitters in the cardiovascular system: are we there yet?

E Arrigo, S Comità, P Pagliaro, C Penna… - International Journal of …, 2023 - mdpi.com
Ischemia is the underlying mechanism in a wide variety of acute and persistent pathologies.
As such, understanding the fine intracellular events occurring during (and after) the …

Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation—a tale of three gases!

L Li, A Hsu, PK Moore - Pharmacology & therapeutics, 2009 - Elsevier
Nitric oxide (NO), carbon monoxide (CO) and hydrogen sulphide (H2S) together make up a
family of biologically active gases (the so-called 'gaseous triumvirate') with an increasingly …

Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease

DJ Polhemus, DJ Lefer - Circulation research, 2014 - Am Heart Assoc
Long recognized as a malodorous and highly toxic gas, recent experimental studies have
revealed that hydrogen sulfide (H2S) is produced enzymatically in all mammalian species …

[图书][B] Carbon monoxide and cardiovascular functions

R Wang - 2001 - taylorfrancis.com
Akin to nitric oxide, carbon monoxide (CO) was initially viewed as a pure toxic gas, yet it has
been recently demonstrated to be an important endogenous molecule of gas that has …

[HTML][HTML] Redox regulation of gasotransmission in the vascular system: A focus on angiogenesis

RK Mistry, AC Brewer - Free Radical Biology and Medicine, 2017 - Elsevier
Reactive oxygen species have emerged as key participants in a broad range of
physiological and pathophysiological processes, not least within the vascular system …