[HTML][HTML] Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients

H Su, S Yao, W Zhao, M Li, J Liu, W Shang… - Acta Pharmacologica …, 2020 - nature.com
Human infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
causes coronavirus disease 2019 (COVID-19) and there is no cure currently. The 3CL …

Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro

H Liu, F Ye, Q Sun, H Liang, C Li, S Li… - Journal of enzyme …, 2021 - Taylor & Francis
COVID-19 has become a global pandemic and there is an urgent call for developing drugs
against the virus (SARS-CoV-2). The 3C-like protease (3CLpro) of SARS-CoV-2 is a …

Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro

H Su, S Yao, W Zhao, M Li, J Liu, WJ Shang, H Xie… - BioRxiv, 2020 - biorxiv.org
Human infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
cause coronavirus disease 19 (COVID-19) and there is currently no cure. The 3C-like …

Epigallocatechin-3-gallate, an active ingredient of Traditional Chinese Medicines, inhibits the 3CLpro activity of SARS-CoV-2

A Du, R Zheng, C Disoma, S Li, Z Chen, S Li… - International journal of …, 2021 - Elsevier
SARS-CoV-2 is the etiological agent responsible for the ongoing pandemic of coronavirus
disease 2019 (COVID-19). The main protease of SARS-CoV-2, 3CLpro, is an attractive …

Chinese herbal medicine: Fighting SARS-CoV-2 infection on all fronts

Z Wang, L Yang - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection causes coronavirus disease 2019 (COVID-19), a highly pathogenic virus …

Discovery of S-217622, a noncovalent oral SARS-CoV-2 3CL protease inhibitor clinical candidate for treating COVID-19

Y Unoh, S Uehara, K Nakahara, H Nobori… - Journal of medicinal …, 2022 - ACS Publications
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths and threatens …

Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening

Y Xiong, GH Zhu, HN Wang, Q Hu, LL Chen, XQ Guan… - Fitoterapia, 2021 - Elsevier
Chymotrypsin-like protease (3CL pro) is a virally encoded main proteinase that is pivotal for
the viral replication across a broad spectrum of coronaviruses. This study aims to discover …

[HTML][HTML] Schaftoside inhibits 3CLpro and PLpro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19

Y Yi, M Zhang, H Xue, R Yu, YO Bao, Y Kuang… - … Pharmaceutica Sinica B, 2022 - Elsevier
It is an urgent demand worldwide to control the coronavirus disease 2019 (COVID-19)
pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Evaluation of medicinal herbs as a potential therapeutic option against SARS‐CoV‐2 targeting its main protease

S Upadhyay, PK Tripathi, M Singh… - Phytotherapy …, 2020 - Wiley Online Library
The COVID‐19 disease caused by the SARS‐CoV‐2 has emerged as a worldwide
pandemic and caused huge damage to the lives and economy of more than hundred …

Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19

H Xu, S Li, J Liu, J Cheng, L Kang… - Proceedings of the …, 2023 - National Acad Sciences
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern,
and effective antiviral reagents are urgently needed. Traditional Chinese medicine theory …