A two-week, randomized, double-masked study to evaluate safety and efficacy of lubricin (150 μg/mL) eye drops versus sodium hyaluronate (HA) 0.18% eye drops …

A Lambiase, BD Sullivan, TA Schmidt, DA Sullivan… - The ocular …, 2017 - Elsevier
Purpose The objective of this clinical trial (NCT02507934) was to assess the efficacy and
safety of recombinant human lubricin as compared to a 0.18% sodium hyaluronate (HA) eye …

Evaluation of clinical outcomes in patients with dry eye disease using lubricant eye drops containing polyethylene glycol or carboxymethylcellulose

S Cohen, A Martin, K Sall - Clinical Ophthalmology, 2013 - Taylor & Francis
Background The purpose of this study was to compare changes in corneal staining in
patients with dry eye after 6 weeks of treatment with Systane® Gel Drops or Refresh …

Demonstration of efficacy in the treatment of dry eye disease with 0.18% sodium hyaluronate ophthalmic solution (vismed, rejena)

R Vogel, RS Crockett, N Oden, TW Laliberte… - American journal of …, 2010 - Elsevier
PURPOSE: To evaluate the efficacy and safety of 0.18% sodium hyaluronate ophthalmic
solution (Rejena, Vismed) compared with its vehicle for the treatment of signs and symptoms …

Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation

WF Davitt, M Bloomenstein, M Christensen… - Journal of ocular …, 2010 - liebertpub.com
Purpose: The effective management of dry eye must include a clinically meaningful
reduction in ocular staining. Evaluations of corneal and conjunctival staining and other …

[HTML][HTML] Evaluation of an enhanced viscosity artificial tear for moderate to severe dry eye disease: A multicenter, double-masked, randomized 30-day study

C Lievens, G Berdy, D Douglass, S Montaquila… - Contact Lens and …, 2019 - Elsevier
Purpose In a randomized, controlled clinical trial, two lubricant artificial tear formulations with
enhanced viscosity were compared: an investigational product at the time, containing …

An open-label evaluation of HP‐Guar gellable lubricant eye drops for the improvement of dry eye signs and symptoms in a moderate dry eye adult population

I Hartstein, S Khwarg, J Przydryga - Current medical research and …, 2005 - Taylor & Francis
Objective: Evaluate the efficacy of a polymer hydroxypropyl guar (HP‐Guar) gellable
lubricant eye drop (Systane* Lubricant Eye Drops) in reducing dry eye signs and symptoms …

Efficacy and safety of dual-polymer hydroxypropyl guar-and hyaluronic acid-containing lubricant eyedrops for the management of dry-eye disease: a randomized …

M Labetoulle, S Schmickler, D Galarreta… - Clinical …, 2018 - Taylor & Francis
Background An artificial-tear formulation containing the dual polymers hydroxypropyl guar
(HPG) and hyaluronic acid (HA) is approved for the treatment of dry-eye disease (DED). The …

Efficacy and safety of sodium hyaluronate/chondroitin sulfate preservative-free ophthalmic solution in the treatment of dry eye: a clinical trial

S Belalcázar-Rey, V Sanchez Huerta… - Current Eye …, 2021 - Taylor & Francis
Purpose: To evaluate the efficacy of a preservative free sodium hyaluronate/chondroitin
sulfate ophthalmic solution (SH/CS-PF) in patients with dry eye disease (DED). Methods …

A randomized, multicenter phase 3 study comparing 2% rebamipide (OPC-12759) with 0.1% sodium hyaluronate in the treatment of dry eye

S Kinoshita, K Oshiden, S Awamura, H Suzuki… - Ophthalmology, 2013 - Elsevier
OBJECTIVE: To investigate the efficacy of 2% rebamipide ophthalmic suspension compared
with 0.1% sodium hyaluronate ophthalmic solution for the treatment of patients with dry eye …

Efficacy of eyedrops containing cross-linked hyaluronic acid and coenzyme Q10 in treating patients with mild to moderate dry eye

EI Postorino, L Rania, E Aragona… - European journal of …, 2018 - journals.sagepub.com
Purpose: Dry eye disease (DED) is a common condition causing substantial burden. A
randomized, controlled, single-masked study was performed in 40 patients with mild to …