We have investigated the role of three IS911‐specified proteins in transposition in vivo: the
products of the upstream (OrfA) and downstream (OrfB) open reading frames, and a …

We find that relatives of the bacterial transposon Tn 7 are widespread in disparate
environments and phylogenetically diverse species. These elements form functionally …

A number of bacterial DNA‐binding proteins, including IS element transposases, act
preferentially in cis. We show below that the degree of preferential cis action by IS 10 …

In vivo recombination was found to occur between plasmid pHS1, a temperature-sensitive
replication mutant of pSC101 carrying tetracycline resistance, and plasmid ColE1 after …

Tn5 is a composite transposon consisting of two IS50 sequences in inverted orientation with
respect to a unique, central region encoding several antibiotic resistances. The IS50R …

Tn10 is a bacterial transposon that transposes through a non-replicative mechanism. This
mode of DNA transposition is widely used in bacteria and is also used by “DNA-based” …

The cellular levels of the alternative sigma factor σ54 of Pseudomonas putida have been
examined in a variety of growth stages and culture conditions with a single-chain Fv …

Overexpression of the Tn5 transposase (Tnp) was found to be lethal to Escherichia coli. This
killing was not caused by transposition or dependent on the transpositional or DNA binding …

Transposable elements induce spontaneous mutations, promote genome rearrangements,
regulate gene expression, and participate in the horizontal spread of genes encoding traits …

Tn 916 and related conjugative transposons are clinically significant vectors for the transfer
of antibiotic resistance among human pathogens, and they excise from their donor …