Multifunctional interpenetrating polymer network hydrogels based on methacrylated alginate for the delivery of small molecule drugs and sustained release of protein

J Zhao, X Zhao, B Guo, PX Ma - Biomacromolecules, 2014 - ACS Publications
Multifunctional injectable thermo-/pH-responsive hydrogels as release systems for the oral
delivery of small molecule drugs and the local delivery of protein are presented. The …

Preparation and controlled drug release characteristics of thermoresponsive PEG/poly (NIPAM-co-AMPS) hydrogels

AK Saikia, S Aggarwal, UK Mandal - International Journal of …, 2013 - Taylor & Francis
Thermosensitive hydrogels were prepared by free radical polymerization of N-
isopropylacrylamide (NIPAM) and 2-acrylamido-2-methylpropanesulphonic acid (AMPS) in …

Biodegradable pH-responsive polyacrylic acid derivative hydrogels with tunable swelling behavior for oral delivery of insulin

X Gao, C He, C Xiao, X Zhuang, X Chen - Polymer, 2013 - Elsevier
Novel biodegradable and pH-sensitive hydrogels composed of four types of pH-sensitive
polyacrylic acid derivatives (PAAD) and a biodegradable poly (l-glutamic acid)(PGA) …

Development of a biocompatible and biodegradable hybrid hydrogel platform for sustained release of ionic drugs

J Wu, X Zhao, D Wu, CC Chu - Journal of Materials Chemistry B, 2014 - pubs.rsc.org
In this study, we reported the development of a new drug encapsulation strategy and a
robust hybrid hydrogel platform for controlled and sustained release of small and large …

Preparation, characterization, swelling and in vitro drug release behaviour of poly [N-acryloylglycine-chitosan] interpolymeric pH and thermally-responsive hydrogels

IM El-Sherbiny, RJ Lins, EM Abdel-Bary… - European Polymer …, 2005 - Elsevier
Novel biodegradable pH-and thermal-responsive interpenetrating polymer network (IPN)
hydrogels were prepared for controlled drug delivery studies. The IPN hydrogels were …

Preparation, properties and controlled release behaviors of pH-induced thermosensitive amphiphilic gels

YY Liu, YH Shao, J Lü - Biomaterials, 2006 - Elsevier
Two pH-induced thermosensitive amphiphilic gels for controlled drug release were
constructed with thermosensitive poly (N-isopropylacrylamide)(PNIPAm) and hydrophobic …

Biodegradable thermoresponsive hydrogels for aqueous encapsulation and controlled release of hydrophilic model drugs

X Huang, TL Lowe - Biomacromolecules, 2005 - ACS Publications
A series of hydrogels with both thermoresponsive and completely biodegradable properties
was developed for aqueous encapsulation and controlled release of hydrophilic drugs in …

Preparation of temperature‐sensitive poly(N‐isopropylacrylamide)/β‐cyclodextrin‐grafted polyethylenimine hydrogels for drug delivery

JT Zhang, YN Xue, FZ Gao, SW Huang… - Journal of applied …, 2008 - Wiley Online Library
In this study, novel thermally sensitive semi‐interpenetrating polymeric network hydrogels
composed of poly (N‐isopropylacrylamide)(PNIPAAm) and β‐cyclodextrin‐grafted …

Synthesis of biodegradable thermo-and pH-responsive hydrogels for controlled drug release

C Zhao, X Zhuang, P He, C Xiao, C He, J Sun, X Chen… - Polymer, 2009 - Elsevier
Novel intelligent hydrogels composed of biodegradable and pH-sensitive poly (l-glutamic
acid)(PGA) and temperature sensitive poly (N-isopropylacrylamide-co-2-hydroxyethyl …

pH-sensitive IPN hydrogel beads of carrageenan-alginate for controlled drug delivery

Z Mohamadnia, MJ Zohuriaan-Mehr… - Journal of Bioactive …, 2007 - journals.sagepub.com
Interpenetrating polymer network (IPN) hydrogel beads of carrageenan-sodium alginate
(Caralgi) were prepared under mild conditions. Betamethasone acetate, as a water-soluble …