Construction and evaluation of the hydroxypropyl methyl cellulose-sodium alginate composite hydrogel system for sustained drug release

Y Hu, S Zhang, D Han, Z Ding, S Zeng… - Journal of polymer …, 2018 - Springer
We prepared a hydroxypropyl methyl cellulose-sodium alginate (HPMC-SA) composite
hydrogel with a membrane covering the semi-interpenetrating network based on a semi …

Controlled drug release from hydrogel nanoparticle networks

G Huang, J Gao, Z Hu, JVS John, BC Ponder… - Journal of Controlled …, 2004 - Elsevier
Monodisperse nanoparticles of poly-N-isopropylacrylamide-co-allylamine (PNIPAM-co-
allylamine) and PNIPAM-co-acrylic acid (PNIPAM-co-AA) were synthesized. The close …

A thermosensitive hydrogel based on biodegradable amphiphilic poly (ethylene glycol)–polycaprolactone–poly (ethylene glycol) block copolymers

CY Gong, ZY Qian, CB Liu, MJ Huang… - Smart materials and …, 2007 - iopscience.iop.org
A series of low molecular weight poly (ethylene glycol)–polycaprolactone–poly (ethylene
glycol)(PEG–PCL–PEG) biodegradable block copolymers were successfully synthesized …

Modeling the effect of physical crosslinking degree of pH and temperature responsive poly (NIPAAm-co-VSA)/alginate IPN hydrogels on drug release behavior

KE Balan, C Boztepe, A Künkül - Journal of Drug Delivery Science and …, 2022 - Elsevier
There is a growing demand to design and development of hydrogel based stimuli
responsive drug-delivery systems due to possess several advantages, namely high drug …

Injectable and biocompatible alginate-derived porous hydrogels cross-linked by IEDDA click chemistry for reduction-responsive drug release application

TT Vu, M Gulfam, SH Jo, SH Park, KT Lim - Carbohydrate Polymers, 2022 - Elsevier
In this work, novel injectable and reduction-responsive hydrogels were successfully
prepared via inverse electron demand Diels-Alder reaction between alginate-norbornene …

[HTML][HTML] Smart Hydrogel Formed by Alginate-g-Poly(N-isopropylacrylamide) and Chitosan through Polyelectrolyte Complexation and Its Controlled Release …

M Liu, J Zhu, X Song, Y Wen, J Li - Gels, 2022 - mdpi.com
Smart hydrogels that can respond to external stimuli such as temperature and pH have
attracted tremendous interest for biological and biomedical applications. In this work, we …

Composite alginate hydrogels: An innovative approach for the controlled release of hydrophobic drugs

E Josef, M Zilberman, H Bianco-Peled - Acta Biomaterialia, 2010 - Elsevier
We present an innovative methodology for the sustained delivery of hydrophobic drugs
using composite hydrogels, prepared by embedding oil-in-water microemulsions in …

Salt-, pH-and temperature-responsive semi-interpenetrating polymer network hydrogel based on poly (aspartic acid) and poly (acrylic acid)

Y Zhao, J Kang, T Tan - Polymer, 2006 - Elsevier
In this study, a novel salt-, pH-and temperature-responsive semi-interpenetrating network
(semi-IPN) hydrogel, composed of poly (aspartic acid)(PAsp) and poly (acrylic acid)(PAAc) …

pH-sensitive interpenetrating network hydrogels based on chitosan derivatives and alginate for oral drug delivery

J Yang, J Chen, D Pan, Y Wan, Z Wang - Carbohydrate polymers, 2013 - Elsevier
Methoxy poly (ethylene glycol) grafted carboxymethyl chitosan (mPEG-g-CMC) and alginate
were chosen as the constituents of hydrogel beads for the construction of an interpenetrating …

pH/temperature-responsive behaviors of semi-IPN and comb-type graft hydrogels composed of alginate and poly (N-isopropylacrylamide)

HK Ju, SY Kim, YM Lee - Polymer, 2001 - Elsevier
Thermo-and pH-sensitive comb-type graft and semi-IPN hydrogels were prepared by using
alginate and poly (N-isopropylacrylamide)(PNIPAAm). Comb-type graft hydrogels are …