[PDF][PDF] The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry

TP Peacock, JC Brown, J Zhou, N Thakur… - …, 2022 - pdfs.semanticscholar.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …

The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein

TP Peacock, JC Brown, J Zhou, N Thakur, K Sukhova… - biorxiv, 2022 - biorxiv.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …

SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium

MM Lamers, AZ Mykytyn, TI Breugem, N Groen… - BioRxiv, 2022 - biorxiv.org
In late 2021, the highly mutated SARS-CoV-2 Omicron variant emerged, raising concerns
about its potential extensive immune evasion, increased transmissibility and pathogenicity …

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

BJ Willett, J Grove, OA MacLean, C Wilkie, N Logan… - MedRxiv, 2022 - medrxiv.org
Vaccination-based exposure to spike protein derived from early SARS-CoV-2 sequences is
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …

SARS-CoV-2 Omicron spike mediated immune escape and tropism shift

B Meng, IATM Ferreira, A Abdullahi, N Goonawardane… - BioRxiv, 2021 - biorxiv.org
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in late 2021 and is characterised
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …

[HTML][HTML] SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion

B Meng, IATM Ferreira, A Abdullahi, A Saito, I Kimura… - BioRxiv, 2021 - biorxiv.org
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in late 2021 and is characterised
by multiple spike mutations across all spike domains. Here we show that compared to the …

[HTML][HTML] SARS-CoV-2 Omicron spike mediated immune escape and tropism shift

R Gupta - Research square, 2022 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in late 2021 and is characterised
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …

Omicron: Master of immune evasion maintains robust ACE2 binding

M Hoffmann, L Zhang, S Pöhlmann - Signal Transduction and Targeted …, 2022 - nature.com
The spike (S) protein of the SARS-CoV-2 Omicron variant is highly mutated but the impact of
these mutations on viral entry into cells and its inhibition by antibodies has been unclear. A …

Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

G Shi, T Li, KK Lai, RF Johnson, JW Yewdell… - Nature …, 2024 - nature.com
Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-
CoV-2 variants of concern worldwide, and gave rise to lineages that continue to spread …

[PDF][PDF] SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses

W Dejnirattisai, J Huo, D Zhou, J Zahradník, P Supasa… - Cell, 2022 - cell.com
On 24 th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B. 1.1.
529 was announced, containing far more mutations in Spike (S) than previously reported …