Study Design. A randomized experimental study. Objective. The aim of this study was to
investigate the therapeutic efficacy and molecular mechanisms of dopamine D1 receptor …

Study design: Randomized experimental study. Objectives: The study aimed to investigate
the therapeutic efficacy and molecular mechanisms of A-68930 in a rat model of spinal cord …

Background Inflammasomes are involved in diverse inflammatory diseases. Previous study
reported that the neurotransmitter dopamine inhibited NLRP3 inflammasome activation via …

Spinal cord injury (SCI) is a serious condition that affects bodily function; however, there is
no effective therapy in clinical practice. MCC950, a selective NOD-like receptor protein-3 …

Background An excessive inflammatory response accompanies the pathogenesis of spinal
cord injury (SCI) and has been found to be promoted by inflammasomes in a variety of …

Alzheimer's disease (AD) is an irreversible neurodegenerative disease characterized by
progressive cognitive dysfunction and memory impairment. Dopamine is an important …

Spinal cord injury (SCI) leads to irreversible functional deficits due to the disruption of axons
and the death of neurons and glial cells. The inflammatory response that occurs in the …

Background: Traumatic Spinal Cord Injury (SCI) is a severe condition usually accompanied
by an inflammatory process that gives rise to uncontrolled local apoptosis and a subsequent …

Objective Dopamine (DA) is a neurotransmitter and chemical mediator, and DA receptors
(particularly DRD1) are present on the majority of immune cells. The aim of this study was to …

Background Spinal cord injury (SCI) is a life-threatening traumatic disorder. Paeonol has
been confirmed to be involved in a variety of diseases. The purpose of this study is to …