Selenium (Se) is an essential dietary component for animals including humans and is
regarded as a protective agent against cancer. Although the mode of anticancer action of Se …

Selenium (Se) acts as an essential trace element in the human body due to its unique
biological functions, particularly in the oxidation-reduction system. Although several clinical …

In vitro and in vivo experimental models clearly demonstrate the efficacy of Se compounds
as anticancer agents, contingent upon chemical structures and concentrations of test …

The essential trace element selenium, which is a crucial cofactor in the most important
endogenous antioxidative systems of the human body, is attracting more and more the …

Background With cancer cells encompassing consistently higher production of reactive
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …

Many experimental models demonstrated that inorganic and organic selenium (Se)
compounds may have an anticancer activity. However, large clinical studies failed to …

An overview highlighting the anti‐cancer potential of (bio‐essential) selenium‐and tellurium‐
containing species, with an emphasis on biological targets and mechanisms of action, is …

The synthesis and anticancer evaluation of novel selenium-nonsteroidal anti-inflammatory
drug (Se-NSAID) hybrid molecules are reported. The Se-aspirin analogue 8 was identified …

Selenium (Se) exerts its anticarcinogenic effects by multiple mechanisms. In the
physiological dosage range, Se appears to function as an antimutagenic agent, preventing …

An adequate selenium (Se) status has for long been considered to prevent the development
of various forms of cancer. However, underlying molecular mechanisms remained unknown …