Pharmacological rescue of nociceptive hypersensitivity and oxytocin analgesia impairment in a rat model of neonatal maternal separation
M Melchior, PE Juif, G Gazzo, N Petit-Demoulière… - Pain, 2018 - journals.lww.com
Oxytocin (OT), known for its neurohormonal effects around birth, has recently been
suggested for being a critical determinant in neurodevelopmental disorders. This …
suggested for being a critical determinant in neurodevelopmental disorders. This …
Experiencing neonatal maternal separation increased pain sensitivity in adult male mice: involvement of oxytocinergic system
H Amini-Khoei, S Amiri, A Mohammadi-Asl… - Neuropeptides, 2017 - Elsevier
Early-life stress adversely affects the development of the brain, and alters a variety of
behaviors such as pain in later life. In present study, we investigated how early-life stress …
behaviors such as pain in later life. In present study, we investigated how early-life stress …
Oxytocin signaling in pain: cellular, circuit, system, and behavioral levels
Originally confined to the initiation of parturition and milk ejection after birth, the
hypothalamic nonapeptide oxytocin (OT) is now recognized as a critical determinant of …
hypothalamic nonapeptide oxytocin (OT) is now recognized as a critical determinant of …
Oxytocin pathways in the intergenerational transmission of maternal early life stress
Severe stress in early life, such as childhood abuse and neglect, constitutes a major risk
factor in the etiology of psychiatric disorders and somatic diseases. Importantly, these long …
factor in the etiology of psychiatric disorders and somatic diseases. Importantly, these long …
[HTML][HTML] Newborn analgesia mediated by oxytocin during delivery
M Mazzuca, M Minlebaev, A Shakirzyanova… - Frontiers in cellular …, 2011 - frontiersin.org
The mechanisms controlling pain in newborns during delivery are poorly understood. We
explored the hypothesis that oxytocin, an essential hormone for labor and a powerful …
explored the hypothesis that oxytocin, an essential hormone for labor and a powerful …
Dysfunctions of brain oxytocin signaling: implications for poor mothering
A Sanson, OJ Bosch - Neuropharmacology, 2022 - Elsevier
Good mothering has profound impact on both the mother's and the young's well-being.
Consequently, experiencing inadequate maternal care–or even neglect–in the first stages of …
Consequently, experiencing inadequate maternal care–or even neglect–in the first stages of …
Intranasal oxytocin administration facilitates the induction of long-term potentiation and promotes cognitive performance of maternally separated rats
Maternal separation (MS) is known to induce permanent changes in the central nervous
system and is associated with increased levels of anxiety and cognitive impairments. The …
system and is associated with increased levels of anxiety and cognitive impairments. The …
Neuroactive steroids attenuate oxytocin stress responses in late pregnancy
JA Russell, PJ Brunton - Neuroscience, 2006 - Elsevier
In late pregnant rats neuroendocrine stress responses, expressed as increased oxytocin
secretion and activation of the hypothalamo–pituitary–adrenal axis, are attenuated. These …
secretion and activation of the hypothalamo–pituitary–adrenal axis, are attenuated. These …
[HTML][HTML] The role of oxytocin and the effect of stress during childbirth: neurobiological basics and implications for mother and child
MH Walter, H Abele, CF Plappert - Frontiers in endocrinology, 2021 - frontiersin.org
The neuropeptide oxytocin acts as a hormone and a neuromodulator, influencing a
multitude of human social behaviors, including reproduction. During childbirth and the …
multitude of human social behaviors, including reproduction. During childbirth and the …
Neuropeptides as neuroprotective agents: Oxytocin a forefront developmental player in the mammalian brain
F Vargas-Martinez, K Uvnäs-Moberg… - Progress in …, 2014 - Elsevier
Oxytocin (OT) plays a major role in the establishment of social bonds. Social bonds are
linked to the activation of cell signaling pathways that promote neurotrophic and synaptic …
linked to the activation of cell signaling pathways that promote neurotrophic and synaptic …