Fundamentals and developments in fluorescence-guided cancer surgery

JSD Mieog, FB Achterberg, A Zlitni… - Nature reviews Clinical …, 2022 - nature.com
Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …

Fluorescence guidance in surgical oncology: challenges, opportunities, and translation

MT Olson, QP Ly, AM Mohs - Molecular imaging and biology, 2019 - Springer
Surgical resection continues to function as the primary treatment option for most solid
tumors. However, the detection of cancerous tissue remains predominantly subjective and …

Latest developments in molecular tracers for fluorescence image-guided cancer surgery

S Hernot, L van Manen, P Debie, JSD Mieog… - The lancet …, 2019 - thelancet.com
Real-time intraoperative guidance is essential during oncological surgery for complete and
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …

Fluorescence image-guided tumour surgery

K Wang, Y Du, Z Zhang, K He, Z Cheng, L Yin… - Nature Reviews …, 2023 - nature.com
Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …

Fluorescent imaging of cancerous tissues for targeted surgery

L Bu, B Shen, Z Cheng - Advanced drug delivery reviews, 2014 - Elsevier
To maximize tumor excision and minimize collateral damage are the primary goals of cancer
surgery. Emerging molecular imaging techniques have made “image-guided surgery” …

[HTML][HTML] Fluorescence-guided surgery

T Nagaya, YA Nakamura, PL Choyke… - Frontiers in …, 2017 - frontiersin.org
Surgical resection of cancer remains an important treatment modality. Despite advances in
preoperative imaging, surgery itself is primarily guided by the surgeon's ability to locate …

Optical principles of fluorescence-guided brain tumor surgery: a practical primer for the neurosurgeon

DY Zhang, S Singhal, JYK Lee - Neurosurgery, 2019 - journals.lww.com
Fluorescence-guided surgery is a rapidly growing field that has produced some of the most
important innovations in surgical oncology in the past decade. These intraoperative imaging …

Molecular probes for fluorescence image-guided cancer surgery

R Ito, M Kamiya, Y Urano - Current Opinion in Chemical Biology, 2022 - Elsevier
In cancer surgery, complete surgical resection of tumor lesions is critical to optimize the
outcome. However, it is sometimes difficult to distinguish the boundary between tumor and …

Oncologic procedures amenable to fluorescence-guided surgery

KE Tipirneni, JM Warram, LS Moore, AC Prince… - Annals of …, 2017 - journals.lww.com
Objective: Although fluorescence imaging is being applied to a wide range of cancers, it
remains unclear which disease populations will benefit greatest. Therefore, we review the …

Fluorescence imaging in surgery

RK Orosco, RY Tsien… - IEEE reviews in biomedical …, 2013 - ieeexplore.ieee.org
Although the modern surgical era is highlighted by multiple technological advances and
innovations, one area that has remained constant is the dependence of the surgeon's vision …