Alzheimer's disease (AD) is one of the most common neurodegenerative diseases
responsible for progressive dementia. Deposition of amyloid-β (Aβ) in the brain is the most …

Alzheimer disease (AD) is a neurodegenerative disease clinically characterized by
progressive cognitive dysfunction. Deposition of amyloid-β (Aβ) peptides is the most …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized
clinically by cognitive decline and memory loss. The pathological features are amyloid-ß …

Many neurodegenerative disorders, including Alzheimer's disease (AD), are strongly
associated with the accumulation of oxidative damage. Transgenic animal models are …

Mitochondrial dysfunction has been proposed to play a pivotal role in neurodegenerative
diseases, including Alzheimer's disease (AD). To address whether mitochondrial …

The purpose of our study was to investigate the effects of the mitochondria-targeted
antioxidants, MitoQ and SS31, and the anti-aging agent resveratrol on neurons from a …

Synaptic pathology and mitochondrial oxidative damage are early events in Alzheimer's
disease (AD) progression. Loss of synapses and synaptic damage are the best correlates of …

Considerable evidence suggests that mitochondrial dysfunction and oxidative stress
contribute to the progression of Alzheimer's disease (AD). We examined the ability of the …

Oxidative stress, likely stemming from dysfunctional mitochondria, occurs before major
cognitive deficits and neuropathologies become apparent in Alzheimer's disease (AD) …

Background: Alzheimer's disease (AD) is the most common neurodegenerative disorder
characterized by cognitive decline and total brain atrophy. Despite the substantial scientific …