Investigating the assembly of the bacterial type III secretion system injectisome by in vivo photocrosslinking
N Singh, S Wagner - International Journal of Medical Microbiology, 2019 - Elsevier
Virulence-associated type III secretion systems serve the injection of bacterial effector
proteins into eukaryotic host cells. These effector proteins modulate host cell biology in order …
proteins into eukaryotic host cells. These effector proteins modulate host cell biology in order …
[HTML][HTML] Recent structural advances towards understanding of the bacterial type III secretion injectisome
J Jenkins, LJ Worrall, NCJ Strynadka - Trends in Biochemical Sciences, 2022 - cell.com
The bacterial injectisome is a structurally conserved, syringe-shaped nanomachine that
spans the Gram-negative envelope and forms a continuous channel for type III secretion of …
spans the Gram-negative envelope and forms a continuous channel for type III secretion of …
Piecing together the type III injectisome of bacterial pathogens
TF Moraes, T Spreter, NCJ Strynadka - Current opinion in structural biology, 2008 - Elsevier
The Type III secretion system is a bacterial 'injectisome'which allows Gram-negative bacteria
to shuttle virulence proteins directly into the host cells they infect. This macromolecular …
to shuttle virulence proteins directly into the host cells they infect. This macromolecular …
Virulence-associated type III secretion systems in Gram-negative bacteria
Virulence-associated bacterial type III secretion systems are multiprotein molecular
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …
Recent insights into type-3 secretion system injectisome structure and mechanism of human enteric pathogens
P Chen, MB Goldberg - Current opinion in microbiology, 2023 - Elsevier
Type-3 secretion system injectisomes are multiprotein complexes that translocate bacterial
effector proteins from the cytoplasm of gram-negative bacteria directly into the cytosol of …
effector proteins from the cytoplasm of gram-negative bacteria directly into the cytosol of …
Transmembrane substrates of type three secretion system injectisomes
The type three secretion system injectisome of Gram-negative bacterial pathogens injects
virulence proteins, called effectors, into host cells. Effectors of mammalian pathogens carry …
virulence proteins, called effectors, into host cells. Effectors of mammalian pathogens carry …
The type III secretion injectisome
GR Cornelis - Nature Reviews Microbiology, 2006 - nature.com
The type III secretion injectisome is a complex nanomachine that allows bacteria to deliver
protein effectors across eukaryotic cellular membranes. In recent years, significant progress …
protein effectors across eukaryotic cellular membranes. In recent years, significant progress …
T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly
The bacterial injectisome is a syringe-shaped macromolecular nanomachine utilized by
many pathogenic Gram-negative bacteria, including the causative agents of plague, typhoid …
many pathogenic Gram-negative bacteria, including the causative agents of plague, typhoid …
Structural overview of the bacterial injectisome
LJ Worrall, E Lameignere, NCJ Strynadka - Current opinion in microbiology, 2011 - Elsevier
The bacterial injectisome is a specialized protein-export system utilized by many pathogenic
Gram-negative bacteria for the delivery of virulence proteins into the hosts they infect. This …
Gram-negative bacteria for the delivery of virulence proteins into the hosts they infect. This …
Cryo-EM structure of the needle filament tip complex of the Salmonella type III secretion injectisome
Type III secretion systems are multiprotein molecular machines required for the virulence of
several important bacterial pathogens. The central element of these machines is the …
several important bacterial pathogens. The central element of these machines is the …