Manganese neurotoxicity and the role of reactive oxygen species
EJ Martinez-Finley, CE Gavin, M Aschner… - Free radical biology and …, 2013 - Elsevier
Manganese (Mn) is an essential dietary nutrient, but an excess or accumulation can be toxic.
Disease states, such as manganism, are associated with overexposure or accumulation of …
Disease states, such as manganism, are associated with overexposure or accumulation of …
Manganese: its role in disease and health
KM Erikson, M Aschner - Met. Ions Life Sci, 2019 - degruyter.com
Manganese is an essential dietary element that functions primarily as a coenzyme in several
biological processes. These processes include, but are not limited to, macronutrient …
biological processes. These processes include, but are not limited to, macronutrient …
[HTML][HTML] Manganese accumulation in the brain via various transporters and its neurotoxicity mechanisms
I Nyarko-Danquah, E Pajarillo, A Digman, KFA Soliman… - Molecules, 2020 - mdpi.com
Manganese (Mn) is an essential trace element, serving as a cofactor for several key
enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and …
enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and …
The impact of manganese on neurotransmitter systems
ATG Soares, A de Castro Silva, AA Tinkov… - Journal of Trace …, 2020 - Elsevier
Abstract Background Manganese (Mn) is a metal ubiquitously present in nature and
essential for many living organisms. As a trace element, it is required in small amounts for …
essential for many living organisms. As a trace element, it is required in small amounts for …
[HTML][HTML] Brain manganese and the balance between essential roles and neurotoxicity
RC Balachandran, S Mukhopadhyay, D McBride… - Journal of Biological …, 2020 - ASBMB
Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …
organs, including the brain. Although its roles as a cofactor in several enzymes and in …
The effects of manganese overexposure on brain health
Manganese (Mn) is the twelfth most abundant element on the earth and an essential metal
to human health. Mn is present at low concentrations in a variety of dietary sources, which …
to human health. Mn is present at low concentrations in a variety of dietary sources, which …
Manganese homeostasis in the nervous system
P Chen, S Chakraborty… - Journal of …, 2015 - Wiley Online Library
Manganese (Mn) is an essential heavy metal that is naturally found in the environment. Daily
intake through dietary sources provides the necessary amount required for several key …
intake through dietary sources provides the necessary amount required for several key …
Manganese and the brain
K Tuschl, PB Mills, PT Clayton - International review of neurobiology, 2013 - Elsevier
Manganese (Mn) is an essential trace metal that is pivotal for normal cell function and
metabolism. Its homeostasis is tightly regulated; however, the mechanisms of Mn …
metabolism. Its homeostasis is tightly regulated; however, the mechanisms of Mn …
The impact of environmental and occupational exposures of manganese on pulmonary, hepatic, and renal functions
D Gandhi, AP Rudrashetti… - Journal of Applied …, 2022 - Wiley Online Library
Manganese (Mn) is an essential trace element for humans, but long‐term environmental or
occupational exposures can lead to numerous health problems. Although many studies …
occupational exposures can lead to numerous health problems. Although many studies …
Manganese: pharmacokinetics and molecular mechanisms of brain uptake
M Aschner, DC Dorman - Toxicological reviews, 2006 - Springer
Manganese is an essential mineral that is found at low levels in virtually all diets.
Manganese ingestion represents the principal route of human exposure, although inhalation …
Manganese ingestion represents the principal route of human exposure, although inhalation …