Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic fat accumulation and is
presently the most common chronic liver disease. However, the mechanisms underlying the …

AIM: To assess the regulatory effect of microRNA-185 (miR-185) on lipid metabolism and the
insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model …

The incidence of nonalcoholic fatty liver disease (NAFLD) and hyperlipidemia, with their
associated risks of endstage liver and cardiovascular diseases, is increasing rapidly due to …

Identification of microRNAs (miRNAs) that regulate lipid metabolism is important to advance
the understanding and treatment of some of the most common human diseases. In the liver …

Non-alcoholic fatty liver disease (NAFLD) affects obesity-associated metabolic syndrome,
which exhibits hepatic steatosis, insulin insensitivity and glucose intolerance. Previous …

MicroRNAs, a class of small non-coding RNAs, are believed to regulate several biological
pathways and processes and are implicated in several diseases. They mostly regulate the …

Despite years of effort, exact pathogenesis of nonalcoholic fatty liver disease (NAFLD)
remains obscure. To gain an insight into the regulatory roles of microRNAs (miRNAs) in …

Background: Hepatic expression of microRNA-107 is ubiquitously upregulated in various
metabolic diseases. In our previous study, we had demonstrated that fatty acid synthase …

Nonalcoholic fatty liver disease (NAFLD) amplifies the risk of various liver diseases, ranging
from simple steatosis to nonalcoholic steatohepatitis, fibrosis, and cirrhosis, and ultimately …

In a microarray study, we found that hepatic miR-291b-3p was significantly increased in
leptin-receptor-deficient type 2 mice (db/db), a mouse model of diabetes. The function of miR …