Therapy of mitochondria-targeted hybrid nanozymes for reactive oxygen species-induced diseases
Z Wang, Z Shen, S Lin, X Mei - Applied Materials Today, 2023 - Elsevier
The development of enzyme mimetics that clear excess mitochondrial reactive oxidative
stress (ROS) could provide effective treatment for a wide variety of diseases. Herein …
stress (ROS) could provide effective treatment for a wide variety of diseases. Herein …
Biomimetic Design of Mitochondria‐Targeted Hybrid Nanozymes as Superoxide Scavengers
Y Zhang, A Khalique, X Du, Z Gao, J Wu… - Advanced …, 2021 - Wiley Online Library
Abstract Development of enzyme mimics for the scavenging of excessive mitochondrial
superoxide (O2•−) can serve as an effective strategy in the treatment of many diseases …
superoxide (O2•−) can serve as an effective strategy in the treatment of many diseases …
Antioxidant activities of metal single-atom nanozymes in biomedicine
Q Zeng, H Zhong, J Liao, Q Huo, B Miao, L Zeng… - Biomaterials …, 2024 - pubs.rsc.org
Nanozymes are a class of nanomaterials with enzyme-like activity that can mimic the
catalytic properties of natural enzymes. The small size, high catalytic activity, and strong …
catalytic properties of natural enzymes. The small size, high catalytic activity, and strong …
[HTML][HTML] A histidine-functionalized ROS scavenging hybrid nanozyme for therapeutic application in Parkinson's disease pathogenesis
Oxidative stress-mediated neurotoxicity is one of the significant molecular consequences in
the progression of neurodegenerative diseases like Parkinson's disease (PD). Although …
the progression of neurodegenerative diseases like Parkinson's disease (PD). Although …
Nanozymes targeting mitochondrial repair in disease treatment
Y Zhang, S Ma, W Chang, W Yu, L Zhang - Journal of Biotechnology, 2024 - Elsevier
Mitochondria are crucial sites for biological oxidation and substance metabolism and plays a
vital role in maintaining intracellular homeostasis. When mitochondria undergo oxidative …
vital role in maintaining intracellular homeostasis. When mitochondria undergo oxidative …
Multi-shell nanocomposites based multienzyme mimetics for efficient intracellular antioxidation
Y Ai, J You, J Gao, J Wang, H Sun, M Ding, Q Liang - Nano Research, 2021 - Springer
Oxidative stress is associated with many acute and chronic inflammatory diseases.
Development of nanomaterial-based enzyme mimetics for reactive oxygen species (ROS) …
Development of nanomaterial-based enzyme mimetics for reactive oxygen species (ROS) …
Incorporation of a biocompatible nanozyme in cellular antioxidant enzyme cascade reverses huntington's like disorder in preclinical model
The potentiality of nano‐enzymes in therapeutic use has directed contemporary research to
develop a substitute for natural enzymes, which are suffering from several disadvantages …
develop a substitute for natural enzymes, which are suffering from several disadvantages …
[HTML][HTML] Rational design and biological application of antioxidant nanozymes
R Tian, J Xu, Q Luo, C Hou, J Liu - Frontiers in chemistry, 2021 - frontiersin.org
Nanozyme is a type of nanostructured material with intrinsic enzyme mimicking activity,
which has been increasingly studied in the biological field. Compared with natural enzymes …
which has been increasingly studied in the biological field. Compared with natural enzymes …
Nanozyme-based medicine for enzymatic therapy: progress and challenges
Q Wang, J Jiang, L Gao - Biomedical Materials, 2021 - iopscience.iop.org
Nanozymes are nanomaterials with enzyme-like characteristics. As a new generation of
artificial enzymes, nanozymes have the advantages of low cost, good stability, simple …
artificial enzymes, nanozymes have the advantages of low cost, good stability, simple …
[HTML][HTML] Recent trends in composite nanozymes and their pro-oxidative role in therapeutics
S Maddheshiya, S Nara - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Nanozymes are inorganic nanostructures whose enzyme mimic activities are increasingly
explored in disease treatment, taking inspiration from natural enzymes. The catalytic ability …
explored in disease treatment, taking inspiration from natural enzymes. The catalytic ability …