Loratadine (LoR) is a highly lipophilic and practically insoluble in water, hence having a low
oral bioavailability. As it is formulated as topical gel, it competitively binds with the receptors …

Objective: To design a controlled topical delivery system of lornoxicam (LX) in order to
enhance skin permeation and treatment efficacy. Nanosponges were selected as a novel …

Owing to its slightly aqueous solubility, loratadine (LOR) is used in high doses in different
marketed formulations to achieve its desirable bioavailability. The aim of this work is to …

Niosomes are non-ionic surfactant nanovesicles, used to entrap both hydrophilic and
hydrophobic drugs. Penetration of encapsulated drugs through niosomal vesicles can …

The unique requirements of poorly water-soluble drug delivery have driven a great deal of
research into new formulations and routes of administration. This study investigates the use …

The objective of the present work was to formulate and evaluate mucoadhesive in situ nasal
gels of loratadine. This drug delivery system may overcome the first-pass metabolism and …

Ranolazine loaded ethosomal system were developed by varying the proportion of soya
lecithin (0.9–1.5% w/v) and ethanol (20–40% w/v). The prepared ethosomal formulations …

The aim of the present work was to assess the feasibility of Acconon MC8-2 EP/NF as a
bioadhesive material for developing controlled release gastroretentive microsponges of …

Hesperetin (HT) is a polyphenolic compound with anti-carcinogenic, tumor necrosis, and
anti-oxidant properties. The present study reports the fabrication, optimization, and …

The present investigation focussed on the development of a novel strategy to enhance the
bioavailability of risedronate sodium, which has poor and erratic absorption. Nanosponges …