Cancer vaccines and immune checkpoint inhibitors (ICIs) function at different stages of the
cancer immune cycle due to their distinct mechanisms of action. Therapeutic cancer …

Although cancer chemotherapy has historically been considered immune suppressive, it is
now accepted that certain chemotherapies can augment tumor immunity. The recent …

Therapeutic cancer vaccines have proven to seldom induce dramatic clinical response
when used alone, and therefore, they are being studied in combination with additional …

Immune checkpoint inhibitors are increasingly drawing much attention in the therapeutic
development for cancer treatment. However, many cancer patients do not respond to …

Introduction: The approval of multiple checkpoint inhibitors (CPIs) for the treatment of
advanced malignancies has sparked an explosion of research in the field of cancer …

Cancer immunotherapy can induce sustained responses in patients with cancers in a broad
range of tissues, however, these treatments require the optimized combined therapeutic …

Introduction: Over the past few years, trials evaluating immunotherapies, particularly immune
checkpoint inhibitors, have revolutionized the standard model of cancer treatment …

Clinical approval of the immune checkpoint blockade (ICB) agents for multiple cancer types
has reinvigorated the long-standing work on cancer vaccines. In the pre-ICB era, clinical …

Simple Summary Immunotherapy helps a person's immune system to target tumor cells.
Recent advances in cancer immunotherapy, including immune checkpoint inhibition …

Conventional chemotherapeutics have been developed into clinically useful agents based
on their ability to preferentially kill malignant cells, generally owing to their elevated …