A topology potential-based method for identifying essential proteins from PPI networks
Essential proteins are indispensable for cellular life. It is of great significance to identify
essential proteins that can help us understand the minimal requirements for cellular life and …
essential proteins that can help us understand the minimal requirements for cellular life and …
Predicting essential proteins based on weighted degree centrality
Essential proteins are vital for an organism's viability under a variety of conditions. There are
many experimental and computational methods developed to identify essential proteins …
many experimental and computational methods developed to identify essential proteins …
Prediction of essential proteins by integration of PPI network topology and protein complexes information
Identifying essential proteins is important for understandingthe minimal requirements for
cellular survival and development. Numerouscomputational methodshave been proposed to …
cellular survival and development. Numerouscomputational methodshave been proposed to …
Discovering essential proteins based on PPI network and protein complex
Most computational methods for identifying essential proteins focus on the topological
centrality of protein-protein interaction (PPI) networks. However, these methods have …
centrality of protein-protein interaction (PPI) networks. However, these methods have …
Identifying essential proteins based on dynamic protein-protein interaction networks and RNA-Seq datasets
X Shang, Y Wang, B Chen - Science China Information Sciences, 2016 - Springer
The identification of essential proteins is not only important for understanding organism
structure on the molecular level, but also beneficial to drug-target detection and genetic …
structure on the molecular level, but also beneficial to drug-target detection and genetic …
Predicting essential proteins by integrating network topology, subcellular localization information, gene expression profile and go annotation data
W Zhang, J Xu, X Zou - IEEE/ACM transactions on …, 2019 - ieeexplore.ieee.org
Essential proteins are indispensable for maintaining normal cellular functions. Identification
of essential proteins from Protein-protein interaction (PPI) networks has become a hot topic …
of essential proteins from Protein-protein interaction (PPI) networks has become a hot topic …
[HTML][HTML] An ensemble framework for identifying essential proteins
Background Many centrality measures have been proposed to mine and characterize the
correlations between network topological properties and protein essentiality. However, most …
correlations between network topological properties and protein essentiality. However, most …
A new algorithm for essential proteins identification based on the integration of protein complex co-expression information and edge clustering coefficient
J Luo, J Wu - International Journal of Data Mining and …, 2015 - inderscienceonline.com
Essential proteins provide valuable information for the development of biology and medical
research from the system level. The accuracy of topological centrality only based methods is …
research from the system level. The accuracy of topological centrality only based methods is …
[HTML][HTML] An iteration method for identifying yeast essential proteins from heterogeneous network
B Zhao, Y Zhao, X Zhang, Z Zhang, F Zhang, L Wang - BMC bioinformatics, 2019 - Springer
Background Essential proteins are distinctly important for an organism's survival and
development and crucial to disease analysis and drug design as well. Large-scale protein …
development and crucial to disease analysis and drug design as well. Large-scale protein …
An iteration method for identifying yeast essential proteins from weighted PPI network based on topological and functional features of proteins
S Li, Z Chen, X He, Z Zhang, T Pei, Y Tan… - IEEE Access, 2020 - ieeexplore.ieee.org
Accumulating studies have indicated that essential proteins play critical roles in numerous
biological processes. With the rapid development of high-throughput technologies, a large …
biological processes. With the rapid development of high-throughput technologies, a large …